Scientometrics
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. May 24, 2025; 16(5): 102747
Published online May 24, 2025. doi: 10.5306/wjco.v16.i5.102747
Knowledge structure analysis and network visualization of tumor-associated macrophages in hepatocellular carcinoma research: A bibliometric mapping
Ping-Li Mo, Ming Lin, Bo-Wen Gao, Shang-Bin Zhang, Jian-Ping Chen
Ping-Li Mo, Shang-Bin Zhang, Jian-Ping Chen, Shenzhen Key Laboratory of Hospital Chinese Medicine Preparation, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518033, Guangdong Province, China
Ming Lin, Department of Hepatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, Guangdong Province, China
Bo-Wen Gao, Department of Traditional Chinese Medicine, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen 518107, Guangdong Province, China
Co-corresponding authors: Ping-Li Mo and Jian-Ping Chen.
Author contributions: Chen JP and Mo PL designed the study, and they contributed equally as co-corresponding authors; Mo PL conducted the data collection and analysis, and wrote the paper; Lin M manipulated the software; Gao BW performed the data analysis and validation; Chen JP and Zhang SB supervised the data analysis and validation and revised the manuscript.
Supported by the Sanming Project of Medicine in Shenzhen, No. SZZYSM202111002; Shenzhen Medical Research Fund, No. B2302008; Shenzhen Science and Technology Program, No. JCYJ20220531091809022, No. JSGG20210802093208023, No. JCYJ20220818103402006, and No. ZDSYS201606081515458; and Traditional Chinese Medicine Bureau of Guangdong Province, No. 20231286.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Ping Chen, Shenzhen Key Laboratory of Hospital Chinese Medicine Preparation, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, No. 1 Fuhua Road, Futian District, Shenzhen 518033, Guangdong Province, China. lycjp@126.com
Received: October 28, 2024
Revised: February 13, 2025
Accepted: April 11, 2025
Published online: May 24, 2025
Processing time: 204 Days and 7.1 Hours
Core Tip

Core Tip: This is the first bibliometric study to investigate the publications on tumor-associated macrophages in hepatocellular carcinoma. The findings revealed knowledge mapping and identified research frontiers within this domain. The primary emphasis of the emerging frontier lay in the regulation of the immunosuppressive attributes exhibited by tumor-associated macrophages within the liver’s distinct immune milieu, with a specific focus on countering immune evasion and reducing immune infiltration.