Sun J, Li HL, Zhou WJ, Ma ZX, Huang XP, Li C. Current status and recent progress of nanomaterials in transcatheter arterial chemoembolization therapy for hepatocellular carcinoma. World J Clin Oncol 2025; 16(4): 104435 [DOI: 10.5306/wjco.v16.i4.104435]
Corresponding Author of This Article
Cheng Li, Professor, Department of Hepatobiliary Pancreatic Hernia Surgery, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, No. 466 Middle Xingang Road, Guangzhou 510317, Guangdong Province, China. 182838li@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jia Sun, Hai-Liang Li, Wen-Jun Zhou, Zeng-Xin Ma, Xiao-Pei Huang, Cheng Li, Department of Hepatobiliary Pancreatic Hernia Surgery, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou 510317, Guangdong Province, China
Author contributions: Sun J contributed to conceptualization; Li HL contributed to literature review and supervision; Sun J and Ma ZX wrote the original draft; Sun J, Li HL, Zhou WJ, and Huang XP reviewed and edited the manuscript; Li C contributed to supervision and guidance.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cheng Li, Professor, Department of Hepatobiliary Pancreatic Hernia Surgery, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, No. 466 Middle Xingang Road, Guangzhou 510317, Guangdong Province, China. 182838li@163.com
Received: December 23, 2024 Revised: February 6, 2025 Accepted: March 5, 2025 Published online: April 24, 2025 Processing time: 95 Days and 21.2 Hours
Core Tip
Core Tip: This article comprehensively discusses the potential of transcatheter arterial chemoembolization combined with various nanomaterials in the treatment of hepatocellular carcinoma. By summarizing the characteristics and applications of liposomes, micellar nanoparticles, hydrogels, metallic nanoparticles, and metal-organic frameworks, it highlights the enhanced therapeutic efficacy and precision offered by nanotechnology. The review also explores the advancements in imaging techniques and the challenges and limitations of integrating nanomaterials into clinical practice. Ultimately, the manuscript provides insights into the promising future of nanomaterial-based transcatheter arterial chemoembolization in hepatocellular carcinoma treatment, with potential for significant clinical impact.
