Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Mar 24, 2025; 16(3): 101274
Published online Mar 24, 2025. doi: 10.5306/wjco.v16.i3.101274
Hepatic arterial infusion pump chemotherapy for colorectal liver metastases: Revisiting traditional techniques to explore new frontiers
Nouredin Messaoudi, Aude Vanlander, Myriam Benhadda, Roza Makarian, Koen Kortbeek, Amy De Haar-Holleman, Andrew A Gumbs
Nouredin Messaoudi, Aude Vanlander, Myriam Benhadda, Roza Makarian, Department of Hepatopancreatobiliary Surgery, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel and Europe Hospitals, Brussels 1090, Brussels-Capital Region, Belgium
Koen Kortbeek, Amy De Haar-Holleman, Department of Oncology, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel, Brussels 1090, Brussels-Capital Region, Belgium
Andrew A Gumbs, Service de Chirurgie Digestive Minimale Invasive, Hôpital Antoine Béclère, Assistance Publique-Hôpitaux de Paris, Clamart 92140, France
Andrew A Gumbs, Department of Surgery, University of Magdeburg, Magdeburg 39130, Saxony-Anhalt, Germany
Author contributions: Messaoudi N and Gumbs AA drafted the manuscript; Makarian R designed the figure; Messaoudi N, Vanlander A, Benhadda M, Makarian R, Kortbeek K, De Haar-Holleman A and Gumbs AA commented on and revised the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Andrew A Gumbs, FACS, MD, MSc, Professor, Service de Chirurgie Digestive Minimale Invasive, Hôpital Antoine Béclère, Assistance Publique-Hôpitaux de Paris, 3 Victoria avenue, Clamart 92140, France. aagumbs@gmail.com
Received: September 9, 2024
Revised: November 14, 2024
Accepted: December 9, 2024
Published online: March 24, 2025
Processing time: 133 Days and 19.7 Hours
Core Tip

Core Tip: This letter to the editor highlights the evolving role of hepatic arterial infusion (HAI) chemotherapy in the treatment of colorectal cancer with colorectal liver metastasis. We explore its integration with modern systemic therapies and emphasize the importance of patient stratification for optimizing outcomes. The findings suggest HAI’s potential to enhance personalized treatment approaches, underscoring the need for further research to refine protocols and overcome technical challenges in clinical practice.