Advanced glycation end products in gastric cancer: A promising future

doi:10.5306/wjco.v15.i9.1117

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Sep 24, 2024; 15(9): 1117-1121
Published online Sep 24, 2024. doi: 10.5306/wjco.v15.i9.1117

Advanced glycation end products in gastric cancer: A promising future

Meng-Hui Wang, Hui Fang, Chuan Xie

Meng-Hui Wang, Hui Fang, Chuan Xie, Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, The Jiangxi Medical College, The Nanchang University, Nanchang 330006, Jiangxi Province, China

Co-first authors: Meng-Hui Wang and Hui Fang.

Author contributions: Wang MH and Fang H wrote the manuscript; Xie C revised the manuscript; all authors have read and approved the final manuscript.

Supported by The National Natural Science Foundation of China, No. 82100599 and No. 81960112; The Jiangxi Provincial Department of Science and Technology, No. 20212ACB216003; The Science and Technology Plan of Jiangxi Provincial Administration of Traditional Chinese Medicine, No.2023Z021; and The Young Talents Project of Jiangxi Provincial Academic and Technical Leaders Training Program for Major Disciplines, No. 20204BCJ23022.

Conflict-of-interest statement: The authors declare no conflict of interest.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Chuan Xie, MD, Chief Doctor, Teacher, Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, The Jiangxi Medical College, The Nanchang University, No.17 Yongwaizheng Street, Nanchang 330006, Jiangxi Province, China. xcsghhz@ncu.edu.cn

Received: March 13, 2024
Revised: July 19, 2024
Accepted: August 2, 2024
Published online: September 24, 2024
Processing time: 168 Days and 23.9 Hours

Core Tip

Core Tip: Gastric cancer is a widespread malignancy that is linked to multiple risk factors. Advanced glycation end products (AGEs) are closely correlated with gastric cancer pathogenesis. Decreasing AGEs levels and minimizing AGEs accumulation may slow gastric cancer progression. Future research endeavours should aim to discover novel interventions to reduce the burden of gastric cancer and improve human health.