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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Aug 24, 2024; 15(8): 982-986
Published online Aug 24, 2024. doi: 10.5306/wjco.v15.i8.982
Published online Aug 24, 2024. doi: 10.5306/wjco.v15.i8.982
Current challenges in the treatment of gliomas: The molecular era
Castalia Fernández, Felipe Couñago, Department of Radiation Oncology, GenesisCare Madrid, Madrid 28043, Spain
Castalia Fernández, Felipe Couñago, Department of Radiation Oncology, Hospital Universitario Vithas La Milagrosa, GenesisCare, Madrid 28010, Spain
Castalia Fernández, Felipe Couñago, Department of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, Madrid 28002, Spain
Juan Zafra-Martín, Department of Radiation Oncology, Hospital Universitario Virgen de la Victoria, Málaga 29010, Spain
Author contributions: Fernández C and Couñago F conceived and performed the study; Fernández C, Couñago F and Zafra-Martín J drafted and revised the paper for important intellectual content; All authors read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Castalia Fernández, MD, Staff Physician, Department of Radiation Oncology, GenesisCare Madrid, Emilio Vargas 16, Madrid 28043, Spain.castaliafer@gmail.com
Received: April 14, 2024
Revised: May 22, 2024
Accepted: July 15, 2024
Published online: August 24, 2024
Processing time: 123 Days and 23.3 Hours
Revised: May 22, 2024
Accepted: July 15, 2024
Published online: August 24, 2024
Processing time: 123 Days and 23.3 Hours
Core Tip
Core Tip: The current trimodal approach including surgery, radiotherapy, and chemotherapy for the treatment of gliomas has benefited from the introduction of molecular diagnosis. However, new challenges have appeared. There is still debate on the best therapeutic option. In this editorial, we focused on the controversial areas in molecular classification and new treatment advances.