Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Apr 24, 2024; 15(4): 548-553
Published online Apr 24, 2024. doi: 10.5306/wjco.v15.i4.548
Elevated cardiovascular risk and acute events in hospitalized colon cancer survivors: A decade-apart study of two nationwide cohorts
Rupak Desai, Avilash Mondal, Vivek Patel, Sandeep Singh, Shaylika Chauhan, Akhil Jain
Rupak Desai, Independent Researcher, Atlanta, GA 30079, United States
Avilash Mondal, Vivek Patel, Department of Internal Medicine, Nazareth Hospital, Philadelphia, PA 19152, United States
Sandeep Singh, Department of Clinical Epidemiology, Biostatistics and Bio-informatics, Amsterdam UMC, Amsterdam 7057, Netherlands
Shaylika Chauhan, Department of Internal Medicine, Geisinger Health System, Wikes-Barre, PA 18702, United States
Akhil Jain, Division of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77079, United States
Author contributions: Desai R, Singh S and Chauhan S conceptualized the methodology of manuscript; Desai R and Mondal A collected resources to write the manuscript; Desai R, Patel V, Singh S, Chauhan S and Jain A reviewed and edited the manuscript; Desai R analyzed the manuscript with software; Desai R, Mondal A, Singh S, Chauhan S and Jain A visualized the results; Singh S, Chauhan S and Jain A supervised the manuscripts. All authors have read and approved the final manuscript.
Institutional review board statement: As the datasets are publicly available and de-identified, they were exempt from institutional review board approval.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at drshaylikachauhan@gmail.com. Participants consent was not obtained but the presented data are anonymized and risk of identification is low.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shaylika Chauhan, MD, FACP, Clinical Assistant Professor (Honorary), Department of Internal Medicine, Geisinger Health System, 1000 E Mountain Blvd, Wikes-Barre, PA 18702, United States. drshaylikachauhan@gmail.com
Received: December 26, 2023
Peer-review started: December 26, 2023
First decision: January 15, 2024
Revised: March 18, 2024
Accepted: March 21, 2024
Article in press: March 21, 2024
Published online: April 24, 2024
Processing time: 118 Days and 4.8 Hours
Core Tip

Core Tip: Colon cancer survivors hospitalized 10 years apart in the United States showed an increased cardiovascular disease risk with an increased risk of acute cardiovascular events (stroke 28%, pulmonary embolism 47%, arrhythmia 41%, and cardiac arrest 63%). Increased screening in this cohort is important.