Review
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Apr 24, 2024; 15(4): 496-522
Published online Apr 24, 2024. doi: 10.5306/wjco.v15.i4.496
Immune pathway through endometriosis to ovarian cancer
Mariana Santos Calmon, Fabian Fellipe Bueno Lemos, Marcel Silva Luz, Samuel Luca Rocha Pinheiro, Luis Guilherme de Oliveira Silva, Gabriel Lima Correa Santos, Gabriel Reis Rocha, Fabrício Freire de Melo
Mariana Santos Calmon, Fabian Fellipe Bueno Lemos, Marcel Silva Luz, Samuel Luca Rocha Pinheiro, Luis Guilherme de Oliveira Silva, Gabriel Lima Correa Santos, Gabriel Reis Rocha, Fabrício Freire de Melo, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Vitória da Conquista 45029-094, Bahia, Brazil
Author contributions: Calmon MS, Lemos FFB and Freire de Melo F contributed to the conceptualization of the manuscript; Calmon MS, Lemos FFB, Silva Luz M, Rocha GR, Correa Santos GL, Silva LGO, Pinheiro SLR, and Freire de Melo F contributed to the manuscript writing; Calmon MS, Lemos FFB, Silva Luz M, Rocha GR, Correa Santos GL, Silva LGO, and Pinheiro SLR wrote the original draft; Calmon MS, Lemos FFB and Freire de Melo F were responsible for manuscript review; Calmon MS, Lemos FFB and Freire de Melo F were responsible for images creation and design; and Freire de Melo F supervised the writing of the original draft.
Conflict-of-interest statement: All authors declare no conflicts of interest regarding the publication of this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fabrício Freire de Melo, PhD, Adjunct Professor, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Estrada do Bem Querer, No. 3293-3391- Candeias, Vitória da Conquista 45029-094, Bahia, Brazil. freiremeloufba@gmail.com
Received: December 15, 2023
Peer-review started: December 15, 2023
First decision: January 15, 2024
Revised: January 29, 2024
Accepted: March 18, 2024
Article in press: March 18, 2024
Published online: April 24, 2024
Core Tip

Core Tip: Current investigations imply a relationship between endometriosis and endometriosis-associated ovarian cancers (EAOCs) through pathways involving oxidative stress, inflammation, and hyperestrogenism. This article endeavors to examine the current data on the molecular events associated with the development of EAOCs from endometriosis, with a particular emphasis on the intricate relationship between the immune response to endometriosis and cancer, including the molecular mechanisms and their implications.