Classificatory updates in verrucous and cuniculatum carcinomas: Insights from the 5th edition of WHO-IARC head and neck tumor classification

doi:10.5306/wjco.v15.i4.464

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Apr 24, 2024 (publication date) through Jan 9, 2025

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World Journal of Clinical Oncology

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Apr 24, 2024; 15(4): 464-467
Published online Apr 24, 2024. doi: 10.5306/wjco.v15.i4.464

Classificatory updates in verrucous and cuniculatum carcinomas: Insights from the 5^th edition of WHO-IARC head and neck tumor classification

Felipe Martins Silveira, Lauren Frenzel Schuch, Ronell Bologna-Molina

Felipe Martins Silveira, Lauren Frenzel Schuch, Ronell Bologna-Molina, Department of Diagnostics in Oral Pathology and Oral Medicine, Faculty of Dentistry, Universidad de la República, Montevideo 1600, Uruguay

Ronell Bologna-Molina, Department of Oral Pathology, Universidad Juarez del Estado de Durango, Durango 13400, Mexico

Author contributions: Silveira FM contributed to conceptualization, investigation, writing – original draft; Schuch LF contributed to investigation, writing – original draft; Bologna-Molina R contributed to supervision, writing/review & editing; all authors have read and approved the final manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Ronell Bologna-Molina, DDS, MSc, PhD, Professor, Department of Diagnostics in Oral Pathology and Oral Medicine, Faculty of Dentistry, Universidad de la República, Montevideo 1600, Uruguay. ronellbologna@hotmail.com

Received: December 9, 2023
Peer-review started: December 9, 2023
First decision: January 28, 2024
Revised: February 2, 2024
Accepted: March 20, 2024
Article in press: March 20, 2024
Published online: April 24, 2024
Processing time: 135 Days and 8.6 Hours

Core Tip

Core Tip: The collaboration between the International Agency for Research on Cancer (IARC) and the World Health Organization (WHO) has produced indispensable 'WHO Blue Books' crucial for standardizing cancer diagnostics. In the 5^th edition of the WHO/IARC classification of head and neck tumors, the 'Oral Cavity and Mobile Tongue' chapter refines its structure, introducing sections for non-neoplastic lesions, epithelial tumors, and tumors with uncertain histogenesis. Notable adjustments in the epithelial tumors section highlight a reorganization based on tumor behavior, offering comprehensive insights into distinct subtypes.