Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Nov 24, 2024; 15(11): 1444-1453
Published online Nov 24, 2024. doi: 10.5306/wjco.v15.i11.1444
Primary pancreatic lymphoma: A case report and review of literature
Marko M Stojanovic, Vesna Brzacki, Goran Marjanovic, Milica Nestorovic, Jelena Zivadinovic, Miljan Krstic, Marko Gmijovic, Ilija Golubovic, Svetlana Jovanovic, Miroslav P Stojanovic, Katarina Terzic
Marko M Stojanovic, Vesna Brzacki, Department of Gastroenterology and Hepatology Clinic, University Clinical Center Nis, Medical Faculty University of Nis, Nis 18000, Serbia
Goran Marjanovic, Immunology, Medical Faculty University of Nis, Nis 18000, Serbia
Milica Nestorovic, Marko Gmijovic, Ilija Golubovic, Svetlana Jovanovic, Miroslav P Stojanovic, Katarina Terzic, Clinic for Digestive Surgery, University Clinical Center, Medical Faculty University of Nis, Nis 18000, Serbia
Jelena Zivadinovic, Clinic of Aneasthesiology and Intensive Therapy, University Clinical Center Nis, University of Nis, Nis 18000, Serbia
Miljan Krstic, Department of Pathology, Medical Faculty University of Nis, Nis 18000, Serbia
Author contributions: Stojanovic MM, Brzacki V, Marjanovic G, Zivadinovic J, Nestorovic M, Gmijovic M, Golubović I and Stojanovic PM treated the patient and designed the case study; Krstic M analyzed the histopathology; Jovanovic S and Terzic K analyzed the recent literature and contributed to writing the manuscript. All authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Miroslav P Stojanovic, MD, PhD, Professor, Clinic for Digestive Surgery, University Clinical Center Nis, Medical Faculty University of Nis, Bul. Dr Zorana Djindjica 60, Nis 18000, Serbia. drmiroslavstojanovic@gmail.com
Received: July 22, 2024
Revised: August 21, 2024
Accepted: September 23, 2024
Published online: November 24, 2024
Processing time: 83 Days and 9.3 Hours
Core Tip

Core Tip: Primary pancreatic lymphoma (PPL) is typically treated with chemotherapy. However, the long-term survival rates are unsatisfactory. Improvements in pancreatic surgery have led to the reevaluation of treatment strategies for PPL. We present the case of a 62-year-old male who was diagnosed with primary pancreatic diffuse large B-cell lymphoma. He was treated with subtotal splenopancreatectomy due to initial imaging suggesting pancreatic adenocarcinoma. He received adjuvant chemotherapy and radiotherapy. After 36 months the patient showed no evidence of disease or recurrence. The potential role of surgery in the treatment of PPL should be considered in the management protocol of early stage lymphoma.