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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Jan 24, 2024; 15(1): 1-4
Published online Jan 24, 2024. doi: 10.5306/wjco.v15.i1.1
Published online Jan 24, 2024. doi: 10.5306/wjco.v15.i1.1
Re-evaluating the role of pelvic radiation in the age of modern precision medicine and systemic therapy
Tao-Wei Ke, Sheng-Chi Chang, William Tzu-Liang Chen, Department of Colorectal Surgery, China Medical University Hospital, Taichung 40402, Taiwan
Tao-Wei Ke, School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan
Yu-Min Liao, Che-Hung Lin, Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, Taichung 40402, Taiwan
William Tzu-Liang Chen, Department of Colorectal Surgery, China Medical University Hsinchu Hospital, Hsinchu 30272, Taiwan
William Tzu-Liang Chen, Ji-An Liang, School of Medicine, College of Medicine, China Medical University, Taichung 40402, Taiwan
Ji-An Liang, Chun-Ru Chien, Department of Radiation Oncology, China Medical University Hospital, Taichung 40402, Taiwan
Co-first authors: Tao-Wei Ke and Yu-Min Liao.
Author contributions: Ke TW and Liao YM contributed equally to this work; Ke TW, Liao YM, Chang SC, Chen WTL, Liang JA, and Chien CR made substantial contribution to the design of the work, to the interpretation of data, and to revise the manuscript; all have read and approve the final manuscript. The choice of these researchers (Ke TW and Liao YM) as co-first authors acknowledges and respects this equal contribution, while recognizing the spirit of teamwork and collaboration of this study. In summary, we believe that designating Ke TW and Liao YM as co-first authors is fitting for our manuscript as it accurately reflects our team's collaborative spirit, equal contributions, and diversity.
Supported by National Science and Technology Council , No. NSTC 112-2314-B-039-048 .
Conflict-of-interest statement: We declared no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Ru Chien, MD, PhD, Doctor, Professor, Department of Radiation Oncology, China Medical University Hospital, No. 91 Hsueh-Shih Road, North District, Taichung 40402, Taiwan. d16181@gmail.com
Received: September 25, 2023
Peer-review started: September 25, 2023
First decision: December 2, 2023
Revised: December 9, 2023
Accepted: December 29, 2023
Article in press: December 29, 2023
Published online: January 24, 2024
Processing time: 120 Days and 3.5 Hours
Peer-review started: September 25, 2023
First decision: December 2, 2023
Revised: December 9, 2023
Accepted: December 29, 2023
Article in press: December 29, 2023
Published online: January 24, 2024
Processing time: 120 Days and 3.5 Hours
Core Tip
Core Tip: Neoadjuvant systemic therapy alone without radiation represents a viable option for locally advanced rectal cancer patients, particularly when organ preservation is not a priority. Nevertheless, it is crucial to engage in multidisciplinary discussions, especially considering the limited long-term experience.