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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Feb 24, 2023; 14(2): 89-98
Published online Feb 24, 2023. doi: 10.5306/wjco.v14.i2.89
Published online Feb 24, 2023. doi: 10.5306/wjco.v14.i2.89
New trends in the surgical management of soft tissue sarcoma: The role of preoperative biopsy
Efstathios T Pavlidis, Theodoros E Pavlidis, 2nd Propedeutic Department of Surgery, Hippocration Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece
Author contributions: Pavlidis TE designed research, contributed new analytic tools, analyzed data and review; Pavlidis ET performed research, analyzed data review and wrote the paper.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Theodoros E Pavlidis, Doctor, PhD, Full Professor, Surgeon, 2nd Propedeutic Department of Surgery, Hippocration Hospital, School of Medicine, Aristotle University of Thessaloniki, Konstantinoupoleos 49, Thessaloniki 54642, Greece.
Received: October 21, 2022
Peer-review started: October 21, 2022
First decision: December 26, 2022
Revised: December 26, 2022
Accepted: January 9, 2023
Article in press: January 9, 2023
Published online: February 24, 2023
Processing time: 122 Days and 8.5 Hours
Peer-review started: October 21, 2022
First decision: December 26, 2022
Revised: December 26, 2022
Accepted: January 9, 2023
Article in press: January 9, 2023
Published online: February 24, 2023
Processing time: 122 Days and 8.5 Hours
Core Tip
Core Tip: The diagnosis and treatment of soft tissue sarcoma are multidisciplinary tasks, and wide surgical resection is an absolute necessity. Modern imaging, especially magnetic resonance imaging, is valuable, and preoperative core needle biopsy is the most indicated and effective diagnostic tool. Its correct planning affects surgical management because the opposite means dissemination of cancer cells into healthy anatomical structures influencing resectability and survival. New therapeutic modalities, including chemoradiation, biological agents and immunotherapy, can improve the outcomes of the main surgical management. In any case, the management policy is personalized.