Retrospective Cohort Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Oct 24, 2022; 13(10): 789-801
Published online Oct 24, 2022. doi: 10.5306/wjco.v13.i10.789
Outcomes after natural orifice extraction vs conventional specimen extraction surgery for colorectal cancer: A propensity score-matched analysis
Isaac Seow-En, Lionel Raphael Chen, Yi-Xin Li, Yun Zhao, Jing-Hui Chen, Hairil Rizal Abdullah, Emile Kwong-Wei Tan
Isaac Seow-En, Lionel Raphael Chen, Yun Zhao, Emile Kwong-Wei Tan, Department of Colorectal Surgery, Singapore General Hospital, Singapore 169608, Singapore
Yi-Xin Li, Department of Surgery, Duke-NUS Graduate Medical School, Singapore 169857, Singapore
Jing-Hui Chen, Hairil Rizal Abdullah, Department of Anaesthesiology, Singapore General Hospital, Singapore 169608, Singapore
Author contributions: Seow-En I conceived the research and study design; Seow-En I, Chen LR, Li YX, and Tan EKW contributed to data acquisition and analysis; Zhao Y performed the statistical analysis; all authors were involved in interpretation of data and writing of the manuscript, as well as editing and revision of the article, read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the SingHealth Institutional Review Board.
Informed consent statement: All natural orifice specimen extraction study participants provided informed written consent prior to study enrolment.
Conflict-of-interest statement: All authors declare no conflict-of-interest.
Data sharing statement: No additional data are available.
STROBE statement: All authors have read the STROBE Statement - checklist of items, and the manuscript was prepared and revised according to the STROBE Statement - checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Isaac Seow-En, FRCS (Ed), MBBS, MMed, Assistant Professor, Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608, Singapore. isaac.seow.en@gmail.com
Received: August 30, 2022
Peer-review started: August 30, 2022
First decision: September 26, 2022
Revised: October 8, 2022
Accepted: October 12, 2022
Article in press: October 12, 2022
Published online: October 24, 2022
Processing time: 50 Days and 21.7 Hours
Core Tip

Core Tip: This paper demonstrates the benefit of reduced port laparoscopic colorectal surgery with natural orifice specimen extraction compared to conventional laparoscopic colorectal surgery. This technique represents a natural progression towards scarless surgery - the holy grail of minimally invasive surgery.