Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Sep 24, 2021; 12(9): 712-724
Published online Sep 24, 2021. doi: 10.5306/wjco.v12.i9.712
Embracing cancer immunotherapy with vital micronutrients
Raymond C-F Yuen, Shiu-Ying Tsao
Raymond C-F Yuen, Department of Occupational and Family Medicine, Hosanna Clinic, Singapore 370051, Singapore
Shiu-Ying Tsao, Department of Clinical Research, Hong Kong SAR Oncology Centre, Hong Kong, China
Author contributions: Yuen RCF and Tsao SY contributed equally to this manuscript.
Conflict-of-interest statement: Both authors declare no potential conflict of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shiu-Ying Tsao, MBBS, Academic Research, Department of Clinical Research, Hong Kong SAR Oncology Centre, Hong Kong, 46-54 Yee Wo Street, 12/F, Causeway Bay, Hong Kong SAR, China. sy_tsao@yahoo.com
Received: March 5, 2021
Peer-review started: March 5, 2021
First decision: May 4, 2021
Revised: June 16, 2021
Accepted: August 3, 2021
Article in press: August 3, 2021
Published online: September 24, 2021
Processing time: 196 Days and 3.7 Hours
Core Tip

Core Tip: Micronutrients in combination may enhance immunotherapy efficacy by immunomodulation and minimizing immune-related adverse events, improve acquired immune response through modification of the tumor microenvironment, enhance gut-microbiota immune functions, boost immune-nutrition function, and improve patient outcome.