Systematic Review
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Feb 24, 2020; 11(2): 74-82
Published online Feb 24, 2020. doi: 10.5306/wjco.v11.i2.74
Abdominal metastases of primary extremity soft tissue sarcoma: A systematic review
Maria Anna Smolle, Andreas Leithner, Gerwin Alexander Bernhardt
Maria Anna Smolle, Andreas Leithner, Gerwin Alexander Bernhardt, Department of Orthopaedics and Trauma, Medical University of Graz, Graz 8036, Austria
Author contributions: All authors contributed to the present manuscript by performing literature review, summarizing data, compiling tables, and writing as well as reviewing the manuscript.
Conflict-of-interest statement: None of the authors has any potential conflicts of interest related to this review to declare.
PRISMA 2009 Checklist statement: The PRISMA 2009 Checklist has been added at the end of the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Gerwin Alexander Bernhardt, FACS, Associate Specialist, Department of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz 8036, Austria. gerwin.bernhardt@medunigraz.at
Received: March 20, 2019
Peer-review started: March 20, 2019
First decision: May 7, 2019
Revised: August 25, 2019
Accepted: December 6, 2019
Article in press: December 6, 2019
Published online: February 24, 2020
Processing time: 307 Days and 19 Hours
Core Tip

Core tip: Incidence of abdominal (AM) and retroperitoneal metastases (RM) in patients with primary extremity soft tissue sarcoma has been reported to be as high as 12.1%, depending on the histological subtypes and screening methods used. Patients undergoing metastasectomy seem to have a clear survival benefit. Consequently, regular abdominal check-ups with abdominal computed tomography-scans, ultrasonography or even whole-body-magnetic resonance imaging are preferable in order to detect AM/RM at an early, potentially resectable stage.