Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Oct 24, 2020; 11(10): 844-853
Published online Oct 24, 2020. doi: 10.5306/wjco.v11.i10.844
Published online Oct 24, 2020. doi: 10.5306/wjco.v11.i10.844
Albumin-bound paclitaxel as new treatment for metastatic cholangiocarcinoma: A case report
Roberto Martin Huertas, Raquel Fuentes-Mateos, Juan Jose Serrano Domingo, Elena Corral de la Fuente, Mercedes Rodríguez-Garrote, Medical Oncology Department, Hospital Universitario Ramon y Cajal, Madrid 28034, Spain
Author contributions: All authors contributed equally to this case report and all of them gave final approval for its publication.
Informed consent statement: The patient gave informed consent and the identifiers have been removed prior to submission for publication.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Roberto Martin Huertas, MD, Medical Oncology Department, Hospital Universitario Ramon y Cajal, Ctra. de Colmenar Viejo km. 9100, Madrid 28034, Spain. robertomartinhuertas@outlook.com
Received: May 4, 2020
Peer-review started: May 4, 2020
First decision: July 25, 2020
Revised: July 31, 2020
Accepted: September 8, 2020
Article in press: September 8, 2020
Published online: October 24, 2020
Peer-review started: May 4, 2020
First decision: July 25, 2020
Revised: July 31, 2020
Accepted: September 8, 2020
Article in press: September 8, 2020
Published online: October 24, 2020
Core Tip
Core Tip: Cholangiocarcinomas are very aggressive tumors. Most patients have advanced-stage disease at presentation and the efficacy of systemic therapies for this setting is limited. Albumin bound paclitaxel (nab-paclitaxel) has been approved in some cancers but not in cholangiocarcinoma. We present a clinical case of metastatic cholangiocarcinoma treatment with second-line nab-paclitaxel and we review the preclinical and clinical evidence about its useful in these tumors.