Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Dec 24, 2019; 10(12): 402-408
Published online Dec 24, 2019. doi: 10.5306/wjco.v10.i12.402
Published online Dec 24, 2019. doi: 10.5306/wjco.v10.i12.402
Intravascular large B-cell lymphoma presenting with altered mental status: A case report
Christopher Robert D’Angelo, Kimberly Ku, Julie Chang, Department of Medicine, Section of Hematology/Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, United States
Jessica Gulliver, Department of Pathology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, United States
Author contributions: D’Angelo CR wrote the manuscript and prepared the figures; Ku K and Chang J were involved in direct patient care for this case report and reviewed/revised the manuscript; Gulliver J performed the pathology review and contributed the pathology images; all authors assisted in preparation and final review of the manuscript.
Informed consent statement: The subject involved in this case report died from complications of his disease and therefore was unable to provide informed consent. A letter was mailed to his next-of-kin describing our intent to submit his case as an anonymous case report, and contact information was provided should the next-of-kin have concerns with publication. We received no such notice.
Conflict-of-interest statement: The authors have no conflicts-of-interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Julie Chang, MD, Assistant Professor, Department of Medicine, Section of Hematology/Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Ave, Madison, WI 53792, United States. jc2@medicine.wisc.edu
Telephone: +1-608-2623970 Fax: +1-608-2624598
Received: March 6, 2019
Peer-review started: March 8, 2019
First decision: April 18, 2019
Revised: August 21, 2019
Accepted: November 17, 2019
Article in press: November 17, 2019
Published online: December 24, 2019
Peer-review started: March 8, 2019
First decision: April 18, 2019
Revised: August 21, 2019
Accepted: November 17, 2019
Article in press: November 17, 2019
Published online: December 24, 2019
Core Tip
Core tip: Early diagnosis is critical to altering the disease course of intravascular large B-cell lymphoma (IVLBCL). A triad of B symptoms, organ dysfunction, and an elevated lactate dehydrogenase should prompt consideration of IVLBCL and early biopsy of affected tissues for rapid diagnosis and treatment. Close communication with pathology in cases of suspected IVLBCL is critical in evaluating for this rare and evasive diagnosis.