Sharma G, Jain A, Sharma P, Sharma S, Rathi V, Garg PK. Giant exophytic renal angiomyolipoma masquerading as a retroperitoneal liposarcoma: A case report and review of literature. World J Clin Oncol 2018; 9(7): 162-166 [PMID: 30425941 DOI: 10.5306/wjco.v9.i7.162]
Corresponding Author of This Article
Pankaj Kumar Garg, MS, DNB, MCh, FACS, Associate Professor, Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Dilshad Garden, Delhi 110095, India. dr.pankajgarg@gmail.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Gopal Sharma, Ayush Jain, Prerit Sharma, Pankaj Kumar Garg, Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi 110095, India
Sonal Sharma, Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi 110095, India
Vinita Rathi, Department of Radiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi 110095, India
Author contributions: Sharma G, Jain A, and Garg PK designed the report; all the authors actively managed the patient; Sharma G, Jain A, and Garg PK collected the patient’s clinical data; Sharma S provided the histopathological images; Rathi V provided the radiological images. All the authors analyzed the case, drafted the manuscript and finally approved it.
Informed consent statement: Consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Pankaj Kumar Garg, MS, DNB, MCh, FACS, Associate Professor, Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Dilshad Garden, Delhi 110095, India. dr.pankajgarg@gmail.com
Telephone: +91-11-22692400 Fax: +91-11-22590495
Received: July 6, 2018 Peer-review started: July 6, 2018 First decision: August 21, 2018 Revised: August 12, 2018 Accepted: October 23, 2018 Article in press: October 23, 2018 Published online: November 10, 2018 Processing time: 126 Days and 3.2 Hours
Abstract
A 42-years-old lady, presented with a large retroperitoneal mass which was preoperatively diagnosed as a retroperitoneal liposarcoma following an image guided core biopsy. She underwent a margin-negative resection of the retroperitoneal mass (multi visceral resection - enbloc excision of the retroperitoneal mass with a left nephrectomy and a segmental descending colectomy). The final histopathological examination of the resected specimen confirmed an exophytic renal angiomyolipoma (AML) which was extending into the retroperitoneum. AML is a rare benign tumor arising most commonly from the kidney. It can sometimes present as a diagnostic challenge as it mimics a retroperitoneal liposarcoma or a fat-containing renal cell carcinomas closely. We present this case to share our experience of managing a case of giant exophytic AML which resembled retroperitoneal liposarcoma closely and resulted into an aggressive surgery.
Core tip: A giant exophytic renal angiomyolipoma (AML) can pose a serious diagnostic challenge and may be confused with a retroperitoneal sarcoma. A discordance of the radiological and core biopsy findings in a suspected case of an exophytic renal AML must lead to re-evaluation of the case and repeat biopsies may further clarify the diagnosis.
