Banys-Paluchowski M, Burandt E, Quaas A, Wilczak W, Geist S, Sauter G, Krawczyk N, Pietzner K, Paluchowski P. Liposarcoma of the breast arising in a malignant phyllodes tumor: A case report and review of the literature. World J Clin Oncol 2015; 6(5): 174-178 [PMID: 26468454 DOI: 10.5306/wjco.v6.i5.174]
Corresponding Author of This Article
Dr. med. Peter Paluchowski, MD, Chief of the Department of Obstetrics and Gynecology, Regio Klinikum Pinneberg, Fahltskamp 74, 25421 Pinneberg, Germany. peter.paluchowski@regiokliniken.de
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Oncol. Oct 10, 2015; 6(5): 174-178 Published online Oct 10, 2015. doi: 10.5306/wjco.v6.i5.174
Liposarcoma of the breast arising in a malignant phyllodes tumor: A case report and review of the literature
Malgorzata Banys-Paluchowski, Eike Burandt, Alexander Quaas, Waldemar Wilczak, Stefan Geist, Guido Sauter, Natalia Krawczyk, Klaus Pietzner, Peter Paluchowski
Malgorzata Banys-Paluchowski, Department of Obstetrics and Gynecology, Marienkrankenhaus Hamburg, 22087 Hamburg, Germany
Eike Burandt, Alexander Quaas, Waldemar Wilczak, Guido Sauter, Department of Pathology, University of Hamburg, 20246 Hamburg, Germany
Stefan Geist, Peter Paluchowski, Department of Obstetrics and Gynecology, Regio Klinikum Pinneberg, 25421 Pinneberg, Germany
Natalia Krawczyk, Department of Obstetrics and Gynecology, University of Duesseldorf, 40225 Duesseldorf, Germany
Klaus Pietzner, Department of Obstetrics and Gynecology, University of Berlin-Charite, 10117 Berlin, Germany
Author contributions: Banys-Paluchowski M and Paluchowski P designed the report; Burandt E, Quaas A, Wilczak W and Sauter G performed the histopathological analyses; Geist S and Krawczyk N collected the patient’s clinical data; Banys-Paluchowski M, Burandt E, Pietzner K and Paluchowski P analyzed the data and wrote the paper.
Institutional review board statement: The article has been approved for publication by the Institutional Review Board of the Regio Klinikum Pinneberg.
Informed consent statement: The patient provided informed written consent prior to publication.
Conflict-of-interest statement: All authors declare that there are no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. med. Peter Paluchowski, MD, Chief of the Department of Obstetrics and Gynecology, Regio Klinikum Pinneberg, Fahltskamp 74, 25421 Pinneberg, Germany. peter.paluchowski@regiokliniken.de
Telephone: +49-4101-217222 Fax: +49-4101-217462
Received: April 22, 2015 Peer-review started: April 28, 2015 First decision: June 29, 2015 Revised: July 17, 2015 Accepted: August 4, 2015 Article in press: August 7, 2015 Published online: October 10, 2015 Processing time: 174 Days and 9.3 Hours
Abstract
Liposarcoma of the breast is a very rare malignant tumor. It can clinically manifest as a palpable breast mass and mimic primary breast cancer. We report an unusual case of a 51-year-old female who presented with an asymptomatic right breast mass, which was histologically diagnosed as well differentiated liposarcoma arisen within malignant phyllodes tumor. The patient underwent breast conserving surgery, received no adjuvant treatment and is disease-free after 2 years. Radiological and histopathological features are presented and described in detail. Data from the literature are presented and therapy recommendations discussed.
Core tip: Liposarcoma is a very rare malignant tumor of the breast and may mimic invasive breast cancer on imaging studies. The definite pathological diagnosis may be challenging.
