Case Report
Copyright ©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Clin Oncol. Aug 10, 2013; 4(3): 75-81
Published online Aug 10, 2013. doi: 10.5306/wjco.v4.i3.75
Angioimmunoblastic T-cell lymphoma-associated pure red cell aplasia with abdominal pain
Jin Tao, Feng-Ping Zheng, Hong Tian, Ying Lin, Jian-Zhong Li, Xiao-Liang Chen, Jian-Ning Chen, Chun-Kui Shao, Bin Wu
Jin Tao, Feng-Ping Zheng, Hong Tian, Ying Lin, Jian-Zhong Li, Xiao-Liang Chen, Bin Wu, Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China
Jian-Ning Chen, Chun-Kui Shao, Department of Pathology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China
Author contributions: Tao J and Zheng FP contributed equally to this work; Tao J, Zheng FP, Tian H, Lin Y, Li JZ, Chen XL, Chen JN, Shao CK and Wu B analyzed the data and diagnosed as well as treated the patient; Tao J and Wu B wrote the paper.
Correspondence to: Bin Wu, MD, PhD, Professor and Chairman, Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou 510630, China. binwu001@hotmail.com
Telephone: +86-20-85253095 Fax: +86-20-85253336
Received: February 19, 2013
Revised: May 23, 2013
Accepted: June 1, 2013
Published online: August 10, 2013
Processing time: 136 Days and 23.8 Hours
Abstract

Angioimmunoblastic T-cell lymphoma (AITL) is a unique type of peripheral T-cell lymphoma with a constellation of clinical symptoms and signs, including weight loss, fever, chills, anemia, skin rash, hepatosplenomegaly, lymphadenopathy, thrombocytopenia and polyclonal hypergammaglobulinemia. The histological features of AITL are also distinctive. Pure red cell aplasia is a bone marrow failure characterized by progressive normocytic anemia and reticulocytopenia without leucopenia or thrombocytopenia. However, AITL with abdominal pain and pure red cell aplasia has rarely been reported. Here, we report a rare case of AITL-associated pure red cell aplasia with abdominal pain. The diagnosis was verified by a biopsy of the enlarged abdominal lymph nodes with immunohistochemical staining.

Keywords: Angioimmunoblastic T-cell lymphoma; Anemia; Pure red cell aplasia; Abdominal pain

Core tip: Angioimmunoblastic T-cell lymphoma (AITL)-associated pure red cell aplasia is a unique type of peripheral T-cell lymphoma with a constellation of clinical symptoms and signs; the histological features of AITL are also distinctive. AITL-associated pure red cell aplasia with abdominal pain has rarely been reported. Here, we report a rare case of AITL-associated pure red cell aplasia with abdominal pain. The diagnosis was verified by a biopsy of the enlarged abdominal lymph nodes with immunohistochemical staining.