Shukla A, Kalayarasan R, Sai Krishna P, Pottakkat B. Remnant pancreatic carcinoma: The current status. World J Clin Oncol 2025; 16(5): 107039 [DOI: 10.5306/wjco.v16.i5.107039]
Corresponding Author of This Article
Ankit Shukla, MD, Assistant Professor, Department of Surgery, Dr Rajendra Prasad Government Medical College, Kangra Chamunda bypass NH-20, Tanda 176001, India. nkitshukla@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Oncol. May 24, 2025; 16(5): 107039 Published online May 24, 2025. doi: 10.5306/wjco.v16.i5.107039
Remnant pancreatic carcinoma: The current status
Ankit Shukla, Raja Kalayarasan, Pothugunta Sai Krishna, Biju Pottakkat
Ankit Shukla, Department of Surgery, Dr Rajendra Prasad Government Medical College, Tanda 176001, India
Raja Kalayarasan, Pothugunta Sai Krishna, Biju Pottakkat, Department of Surgical Gastroenterology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry 605006, India
Author contributions: Shukla A and Kalayarasan R contributed to the conceptualization, writing, and editing of this manuscript; Sai Krishna P and Pottakkat B contributed to the article screening and writing; Shukla A, Kalayarasan R, and Sai Krishna P contributed to the literature search; All authors read and agreed to the published version of the manuscript.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ankit Shukla, MD, Assistant Professor, Department of Surgery, Dr Rajendra Prasad Government Medical College, Kangra Chamunda bypass NH-20, Tanda 176001, India. nkitshukla@gmail.com
Received: March 13, 2025 Revised: March 31, 2025 Accepted: April 11, 2025 Published online: May 24, 2025 Processing time: 66 Days and 18.3 Hours
Abstract
Pancreatic carcinoma is one of the most lethal malignancies and has a dismal prognosis. However, advances in diagnostic modalities and better multidisciplinary management have contributed to improved survival in these patients. Of late, various recurrence patterns have been observed; the most common of them being distant metastasis followed by the pancreatic bed and lymph node recurrence. Recurrence in the remnant pancreas is on the rise due to improved survival in patients who previously underwent surgery for pancreatic cancer. Total remnant pancreatectomy is an appealing option in resectable remnant pancreatic carcinoma without distant metastasis. It is an entity showing an increasing incidence and demanding further in-depth studies to elucidate the exact pathological mechanism and to establish appropriate management protocols.
Core Tip: The incidence of remnant pancreatic cancer is increasing as advances in diagnostic modalities and better multidisciplinary management have contributed to improved survival in patients with pancreatic cancer. Recognition of various genetic factors may help in the early detection of remnant pancreatic carcinoma and provide better management. Recent trends show a shift towards surgical management of remnant pancreatic cancer. However, managing remnant pancreatic carcinoma needs further detailed introspection and research to optimize outcomes.
