Fu B, Hu L, Ji H, Hou YF. New research progress of sarcopenia in surgically resectable malignant tumor diseases. World J Clin Oncol 2025; 16(4): 100309 [DOI: 10.5306/wjco.v16.i4.100309]
Corresponding Author of This Article
Ya-Feng Hou, Department of Hepatobiliary Surgery, Tongling People's Hospital (Tongling Hospital Affiliated to Bengbu Medical University), No. 468 Bijiashan Road, Tongguan District, Tongling 244000, Anhui Province, China. 19855755501@163.com
Research Domain of This Article
Surgery
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Oncol. Apr 24, 2025; 16(4): 100309 Published online Apr 24, 2025. doi: 10.5306/wjco.v16.i4.100309
New research progress of sarcopenia in surgically resectable malignant tumor diseases
Bing Fu, Lei Hu, Hui Ji, Ya-Feng Hou
Bing Fu, Lei Hu, Hui Ji, Ya-Feng Hou, Department of Hepatobiliary Surgery, Tongling People's Hospital (Tongling Hospital Affiliated to Bengbu Medical University), Tongling 244000, Anhui Province, China
Author contributions: Fu B and Hu L prepared this manuscript; Ji H performed the literature research; Hou YF played indispensable roles in the study design and manuscript preparation as the corresponding authors; Fu B conceptualized, designed and supervised the whole process of the study; Hu L was responsible for language polishing and literature search; this collaboration between Ji H and Hou YF is crucial for the publication of this manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ya-Feng Hou, Department of Hepatobiliary Surgery, Tongling People's Hospital (Tongling Hospital Affiliated to Bengbu Medical University), No. 468 Bijiashan Road, Tongguan District, Tongling 244000, Anhui Province, China. 19855755501@163.com
Received: August 13, 2024 Revised: January 23, 2025 Accepted: March 6, 2025 Published online: April 24, 2025 Processing time: 225 Days and 2.4 Hours
Abstract
With the aging global population, the decline in muscle mass and function among the elderly has emerged as a significant concern. This systemic progressive generalized loss of muscle function and mass is referred to as sarcopenia (SP). In recent years, a growing number of studies have investigated SP, revealing that many tumor diseases, especially in the digestive system, promote its occurrence due to the influence of the disease itself, diet, and other factors. Moreover, SP patients tend to have poorer postoperative recovery. At present, many diagnostic methods have been developed for SP, but no unified standard has been established. Furthermore, the cutoff values of many diagnostic methods for different populations are still in the exploratory stage, and additional clinical studies are required to explore these issues. This article comprehensively and systematically summarizes the diagnostic methods and criteria mentioned in previous research, focusing on the impact of SP on post-surgical patients with various malignant tumors.
Core Tip: Nowadays, more and more people have begun to pay attention to sarcopenia (SP), especially whether patients with SP before surgery have an impact on their short, long-term results after surgery is the focus of current research. Previously, we found that the diagnostic methods and diagnostic criteria of SP were quite different, and the incidence of SP was also different. This article provides a comprehensive review of the current relationship between SP and cancer.
