Implications of genetic testing and informed consent before and after genetic testing in individuals with cancer
Priyanka Kumar, David J Benjamin, Sourat Darabi, Goetz Kloecker, Arash Rezazadeh Kalebasty
Priyanka Kumar, Department of Hematology and Medical Oncology, Harbor-UCLA Medical Center, Torrance, CA 90502, United States
David J Benjamin, Department of Medical Oncology, Hoag Family Cancer Institute, Newport Beach, CA 92663, United States
Sourat Darabi, Department of Precision Medicine, Hoag Family Cancer Institute, Newport Beach, CA 92663, United States
Goetz Kloecker, Department of Hematology and Medical Oncology, University of Louisville, Louisville, KY 40202, United States
Arash Rezazadeh Kalebasty, Department of Hematology and Medical Oncology, University of California-Irvine, Orange, CA 92868, United States
Author contributions: Kumar P, Benjamin DJ, Darabi S, Kloecker G, and Rezazadeh Kalebasty A designed the research study, performed the research, analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: Kumar P has no disclosures; Benjamin DJ has the following disclosures: Consulting or advisory role: Astellas, Eisai, and Seagen; Speakers’ bureau: Merck; Travel and accommodations: Merck; Darabi S has the following disclosures: Consulting/advisory: Oncolens, Bayer, and BostonGene; Kloecker G has the following disclosures: Speakers’ bureau/advisory: Bristol Myers Squibb, AstraZeneca, Regeneron, Sanofi, Genentech, Novartis, and EMD Serono; Rezazadeh Kalebasty A has the following disclosures: Stock and other ownership interests: ECOM medical; Consulting or advisory role: Exelixis, AstraZeneca, Bayer, Pfizer, Novartis, Genentech, Bristol Myers Squibb, EMD Serono, Immunomedics, and Gilead Sciences; Speakers' bureau: Janssen, Astellas Medivation, Pfizer, Novartis, Sanofi, Genentech/Roche, Eisai, AstraZeneca, Bristol Myers Squibb, Amgen, Exelixis, EMD Serono, Merck, Seattle Genetics/Astellas, Myovant Sciences, Gilead Sciences, and AVEO; Research funding: Genentech, Exelixis, Janssen, AstraZeneca, Bayer, Bristol Myers Squibb, Eisai, Macrogenics, Astellas Pharma, BeyondSpring Pharmaceuticals, BioClin Therapeutics, Clovis Oncology, Bavarian Nordic, Seattle Genetics, Immunomedics, Epizyme; Travel, accommodations, and expenses: Genentech, Prometheus, Astellas Medivation, Janssen, Eisai, Bayer, Pfizer, Novartis, Exelixis, and AstraZeneca.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: David J Benjamin, MD, Doctor, Department of Medical Oncology, Hoag Family Cancer Institute, 1 Hoag Drive, Building 41, Newport Beach, CA 92663, United States. david.benjamin@hoag.org
Received: March 28, 2024
Revised: July 15, 2024
Accepted: July 23, 2024
Published online: August 24, 2024
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