Kumar A, Sarangi Y, Gupta A, Sharma A. Gallbladder cancer: Progress in the Indian subcontinent. World J Clin Oncol 2024; 15(6): 695-716 [PMID: 38946839 DOI: 10.5306/wjco.v15.i6.695]
Corresponding Author of This Article
Ashok Kumar, FACS, FASCRS, FICS, FRCS, FRCS (Ed), MBBS, MCh, MS, Full Professor, Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India. doc.ashokgupta@gmail.com
Research Domain of This Article
Oncology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Ashok Kumar, Yajnadatta Sarangi, Annapurna Gupta, Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, Uttar Pradesh, India
Aarti Sharma, Division of Haematology, Mayo Clinic Arizona, Phoenix, AZ 85054, United States
Author contributions: Kumar A designed the concept, revised and edited the manuscript; Sarangi Y and Gupta A jointly wrote the manuscript; Sharma A helped in literature search.
Conflict-of-interest statement: Dr. Kumar has nothing to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ashok Kumar, FACS, FASCRS, FICS, FRCS, FRCS (Ed), MBBS, MCh, MS, Full Professor, Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India. doc.ashokgupta@gmail.com
Received: February 28, 2024 Revised: April 25, 2024 Accepted: May 15, 2024 Published online: June 24, 2024 Processing time: 116 Days and 21.2 Hours
Abstract
Gallbladder cancer (GBC) is one of the commonest biliary malignancies seen in India, Argentina, and Japan. The disease has dismal outcome as it is detected quite late due to nonspecific symptoms and signs. Early detection is the only way to improve the outcome. There have been several advances in basic as well as clinical research in the hepatobiliary and pancreatic diseases in the West and other developed countries but not enough has been done in GBC. Therefore, it is important and the responsibility of the countries with high burden of GBC to find solutions to the many unanswered questions like etiopathogenesis, early diagnosis, treatment, and prognostication. As India being one of the largest hubs for GBC in the world, it is important to know how the country has progressed on GBC. In this review, we will discuss the outcome of the publications from India highlighting the work and the developments taken place in past several decades both in basic and clinical research.
Core Tip: This review is important to know the work done on gallbladder cancer from the country with high incidence of the disease and struggling to do its best. Research outcome may help to compare with the work being done in rest of the world and for the future collaborative research to find way for early diagnosis and to improve the treatment outcome of this aggressive disease.
