Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. May 24, 2024; 15(5): 664-666
Published online May 24, 2024. doi: 10.5306/wjco.v15.i5.664
Integrating disulfidptosis-related long noncoding RNAs in colorectal cancer prognosis: A path to precision medicine
Shi-Yan Zhang
Shi-Yan Zhang, Department of Clinical Laboratory, Fuding Hospital, Fujian University of Traditional Chinese Medicine, Fuding 355200, Fujian Province, China
Author contributions: Zhang SY wrote and edited the manuscript.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shi-Yan Zhang, MD, Director, Doctor, Department of Clinical Laboratory, Fuding Hospital, Fujian University of Traditional Chinese Medicine, No. 120 South Road of Old City, Fuding 355200, Fujian Province, China. myebox@139.com
Received: February 2, 2024
Revised: March 5, 2024
Accepted: April 9, 2024
Published online: May 24, 2024
Processing time: 108 Days and 23.2 Hours
Abstract

This commentary explores the burgeoning field of disulfidptosis-related long noncoding RNAs (lncRNAs) in the prognosis and therapeutic targeting of colorectal cancer (CRC). By evaluating recent research, including the pivotal study "Predicting colorectal cancer prognosis based on long noncoding RNAs of disulfidptosis genes" by Wang et al, this analysis underscores the critical role of lncRNAs in deciphering the molecular complexities of CRC. Highlighting the innovative methodologies and significant findings, I discuss the implications for patient survival, therapeutic response, and the potential of lncRNAs as biomarkers for precision medicine. The integration of bioinformatics, clinical databases, and molecular biology in these studies offers a promising avenue for advancing CRC treatment strategies and improving patient outcomes.

Keywords: Colorectal cancer; Disulfidptosis; Long noncoding RNAs; Prognosis; Precision medicine

Core Tip: This commentary emphasizes the novel role of disulfidptosis-related long noncoding RNAs (lncRNAs) in colorectal cancer prognosis. Focusing on the intersection of genetic research and clinical practice, it highlights how the study of lncRNAs can facilitate the development of targeted therapies and prognostic models. The critical evaluation of recent research underscores the potential of lncRNAs as biomarkers and therapeutic targets, marking a significant step towards personalized medicine in colorectal cancer treatment.