Rhabdomyolysis after midazolam administration in a cirrhotic patient treated with atorvastatin

Table 1 Biochemical analysis on different days

	ER	Before EGDS	1st day after EGDS	2nd day after EGDS	6th day after EGDS	ICU
ALT (UI/L)	146	52	70	130	207	827
AST (UI/L)	125	117	191	240	927	2075
Total bilirubin (mg/dL)	1.2	2.73	3.39	4.51	6.1	7.44
Direct bilirubin (mg/dL)	0.2	1.86	2.12	3.01	3.8	5.87
INR	1.75	1.7	1.58	1.6	1.68	6.11
Fibrinogen (g/L)	3.52	-	-	-	-	0.58
Platelets (mm3)	115	54	49	45	70	40
D-dimer (ng/mL)	2557	-	-	-	-	9000
ATIII (%)	-	-	-	-	-	20
Myoglobine (ng/mL)	175	198	22.899	25.981	> 30.000	> 30.000
CK (U/L)	81	95	3.298	5.876	38.289	89
CK-MB (ng/mL)	4.2	4.1	14.01	25.03	73.59	68.72
Troponin T HS (mg/L)	0.022	0.025	0.061	0.043	0.189	1.53
LDH (UI/L)	240	286	358	470	1603	2084
Creatinine (mg/dL)	1.1	1.3	1.3	1.3	3.14	3.8
BUN (mg/dL)	45	60	61	59	161	78
Calcium (mg/dL)	8.8	8.4	-	-	6.7	4.4
Diuresis (cc)	-	2000	1300	1000	150	300
BP (mmHg)	90/50	115/60	105/55	95/60	75/50	60/40

EGDS: Esophagogastroduodenoscopy; ICU: Intensive care unit; ALT: Alanine transaminase; AST: Aspartate aminotransferase; ATIII: Antithrombin III; CK: Creatine kinase; INR: International normalized ratio; Troponin T HS: High sensitivity troponin T; LDH: Lactate dehydrogenase; BUN: Blood urea nitrogen; BP: Blood pressure; ER: Emergency room.