Castor oil as booster for colon capsule endoscopy preparation reduction: A prospective pilot study and patient questionnaire

Table 1 Modified colon capsule endoscopy regimen using castor oil as booster

Modified colon capsule endoscopy regimen
Day before endoscopy	21:00	Magnesium citrate P 50 g + water 180 mL
Day of endoscopy	06:00	PEG 1000 mL + water 500 mL
	09:00	Patient comes to the hospital
	09:30	Capsule ingestion, intravenous metoclopramide 10 mg
	10:00	Patient goes home after the capsule reaches the duodenum
	When patient reaches home	Castor oil 20 mL, PEG 500 mL + water 250 mL
	1 h later	PEG 500 mL + water 250 mL
	2 h later	Magnesium citrate 50 g + water 180 mL
	2 h later	Castor oil 20 mL

PEG: Polyethylene glycol.

Table 2 Patient characteristics (n = 17)

Characteristics
Age (yr)
mean ± SD	59.5 ± 16.8
Range	37-80
Sex, n (%)
Male	3 (18)
Female	14 (82)
History of abdominal surgery, n (%)	7 (41)
Reason for colon capsule endoscopy, n (%)
Abdominal pain	5 (29)
Constipation	5 (29)
Elevation of tumor marker	2 (12)
Follow-up examination after polypectomy	2 (12)
Anemia	1 (6)
Bloody stool	1 (6)
Follow-up after colon cancer surgery	1 (6)

Three patients were unable to take castor oil.

Table 3 Results of colon capsule endoscopy (n = 17)

Variables	n (%) or mean (range)
Capsule excretion rate within battery life	15 (88)
Large bowel transit time (min)	236 (16-725)
Cases within 60 min	5 (29)
Cleansing level (overall)	12 (70)
Excellent	6
Good	6
Fair	5
Poor	0
Polyp detection rate	14 (82)

Table 4 Colon capsule endoscopy detection

	Disorder	No disorder
Detection of adenoma ≥ 6 mm
Positive test result	True positive: 10	False positive: 1
Negative test result	False negative: 3	True negative: 3
Sensitivity, 76.9%; Specificity, 75.0%; Diagnostic accuracy, 76.5%
Detection of adenoma ≤ 5 mm
Positive test result	True positive: 2	False positive: 1
Negative test result	False negative: 3	True negative: 3
Sensitivity, 50.0%; Specificity, 66.7%; Diagnostic accuracy, 55.6%
Detection of diverticulums
Positive test result	True positive: 4	False positive: 0
Negative test result	False negative: 0	True negative: 13
Sensitivity, 100%; Specificity, 100%; Diagnostic accuracy, 100%