Copyright
©The Author(s) 2020.
World J Gastrointest Pharmacol Ther. Apr 10, 2020; 11(1): 1-7
Published online Apr 10, 2020. doi: 10.4292/wjgpt.v11.i1.1
Published online Apr 10, 2020. doi: 10.4292/wjgpt.v11.i1.1
Nanomaterials | Example | Function |
Nanoparticles (NPs) | Silica NPs | Photobiological imaging research[24] MRI contrast agent[25] |
Albumin NPs | Wrap anti-proliferation drug (PvD) to target cancer cell[26] | |
Delivery NPs | Safely deliver Gemcitabine to tumor cells and eliminate toxic effects on normal cells[27] | |
Quantum dots (QDs) | Ag2Se QDs | Image pancreatic cancer (PC) in vivo[28] |
CTC QDs | Identify CD24+ and CD133+ to detect CTCs[29] | |
ZnO QDs | Better detection of CA19-9 and PC cell[30] | |
Carbon nanotubes (CNTs) | CA19-9 CNTs | Construct a novel immune sensor and more efficient detection of early PC[31] |
Multi-walled CNTs | Built genetic fingerprints of PC[32] | |
Gold nanoparticles | PEGAuNPs | Effectively deliver drugs to tumor cells |
Further suppressing cancer cell proliferation and reducing the toxicity to normal cells[33] | ||
Improvement in the efficacy of photothermal chemotherapy in PC[34] | ||
Liposome | Collagenase liposome | Prolonging drug release rate at the target site, and effectively improving the efficacy of the drug[35] |
Gemcitabine liposome | Local hyperthermia with liposomes combined with gemcitabine induce cell death and the formation of apoptotic areas[37] |
- Citation: Wang J, He ZW, Jiang JX. Nanomaterials: Applications in the diagnosis and treatment of pancreatic cancer. World J Gastrointest Pharmacol Ther 2020; 11(1): 1-7
- URL: https://www.wjgnet.com/2150-5349/full/v11/i1/1.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v11.i1.1