Wang J, He ZW, Jiang JX. Nanomaterials: Applications in the diagnosis and treatment of pancreatic cancer. World J Gastrointest Pharmacol Ther 2020; 11(1): 1-7 [PMID: 32405438 DOI: 10.4292/wjgpt.v11.i1.1]
Corresponding Author of This Article
Jian-Xin Jiang, PhD, Professor, Department of Hepatic-Biliary Surgery, Renmin Hospital of Wuhan University, 99 Ziyang Road, Wuhan 430060, Hubei Province, China. jjx731003@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Pharmacol Ther. Apr 10, 2020; 11(1): 1-7 Published online Apr 10, 2020. doi: 10.4292/wjgpt.v11.i1.1
Nanomaterials: Applications in the diagnosis and treatment of pancreatic cancer
Jie Wang, Zhi-Wei He, Jian-Xin Jiang
Jie Wang, Zhi-Wei He, Jian-Xin Jiang, Department of Hepatic-Biliary Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China
Author contributions: Jiang JX design of the study; Wang J conducted this review, and manuscript production; Wang J and He ZW provided expert opinion and approved the final manuscript.
Supported byJoint Funds of the National Natural Science Foundation of China, No. 81871965.
Conflict-of-interest statement: All authors declare no conflicting interests related to this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jian-Xin Jiang, PhD, Professor, Department of Hepatic-Biliary Surgery, Renmin Hospital of Wuhan University, 99 Ziyang Road, Wuhan 430060, Hubei Province, China. jjx731003@163.com
Received: December 31, 2019 Peer-review started: December 31, 2019 First decision: February 19, 2020 Revised: March 15, 2020 Accepted: March 28, 2020 Article in press: March 30, 2020 Published online: April 10, 2020 Processing time: 100 Days and 4.2 Hours
Abstract
Pancreatic cancer (PC) remains one of the leading causes of cancer-related death in human sowing to missed early and effective diagnosis. The inability to translate research into clinical trials and to target chemotherapy drugs to tumors is a major obstacle in PC treatment. Compared with traditional cancer detection methods, the method combining existing clinical diagnosis and detection systems with nanoscale components using novel nanomaterials shows higher sensitivity and specificity. Nanomaterials can interact with biological systems to efficiently and accurately detect and monitor biological events during diagnosis and treatment. With the advance of experimental and engineering technology, more nanomaterials will begin the transition to clinical trials for their validation. This paper describes a number of nanomaterials used in the diagnosis and treatment of PC.
Core tip: Pancreatic cancer remains one of the leading causes of cancer-related death in humans owing to missed early and effective diagnosis. Nanomaterials can interact with biological systems to efficiently and accurately detect and monitor biological events during diagnosis and treatment in pancreatic cancer.
