Nutritional status as a predictor of hospitalization in inflammatory bowel disease: A review

Table 1 Five studies on nutritional status as a predictor of hospitalization in patients with inflammatory bowel disease

Author	Study design/study population	Main results
Blain et al[4], 2002	Retrospective study, follow-up	3% (62) were obese
	2065 patients of any age with CD: 62 obese vs 124 non-obese, matched by age, sex, disease location and date of diagnosis of CD	Patients with obese CD had a higher chance of hospitalization than non-obese patients (OR = 2.35, 95%CI: 1.56-3.52)
Flores et al[5], 2015	Retrospective study, follow-up	Obese and overweight patients are less likely to experience hospitalization than the group with low / adequate BMI (42% vs 44% vs 66%, P < 0.001)
	518 patients with IBD divided into obese (BMI ≥ 30 kg/m²), overweight (25-29.9 kg/m²), eutrophic (18.5-24.9 kg/m²) and low weight (< 18.5 kg/m²)
Seminerio et al[6], 2015	Prospective study	There was no association between increased BMI and hospitalization in patients with IBD, in both those with CD and UC (P = 0.396)
	1494 patients with IBD
Ananthakrishnan et al[7], 2010	Retrospective study cohort	Severe hospitalizations were more associated with anemia (20.8% vs 15.1%, P < 0.001) and malnutrition (8.7% vs 2.3%, P < 0.001)
	6169 patients with CD
Gajendran et al[8], 2016	Cross-sectional study (2 yr)	There is an association between malnutrition and hospitalization of patients diagnosed with IBD (OR = 6.29, 95%CI: 5.84–6.78)
	Patients diagnosed with IBD
	Estimated number of 109392 annual visits with a primary diagnosis of IBD

CD: Crohn’s disease; UC: Ulcerative colitis; IBD: Inflammatory bowel disease; BMI: Body mass index.