Retrospective Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Aug 6, 2017; 8(3): 180-185
Published online Aug 6, 2017. doi: 10.4292/wjgpt.v8.i3.180
Use of proton pump inhibitors in general practice
Cesare Tosetti, Ilaria Nanni
Cesare Tosetti, Ilaria Nanni, Health Agency of Bologna, 40046 Alto Reno Terme, Italy
Author contributions: Tosetti C and Nanni I contributed equally in the study design, literature reviewing and data evaluation; Tosetti C wrote the paper with the critical contribution of Nanni I.
Conflict-of-interest statement: No financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Cesare Tosetti, MD, General Practitioner, Health Agency of Bologna, Via Rosselli 21, Porretta Terme, 40046 Alto Reno Terme, Italy. tosetti@libero.it
Telephone: +39-338-3902526 Fax: +39-534-21493
Received: December 28, 2016
Peer-review started: December 29, 2016
First decision: March 13, 2017
Revised: April 18, 2017
Accepted: July 14, 2017
Article in press: July 17, 2017
Published online: August 6, 2017
Processing time: 215 Days and 0.7 Hours
Core Tip

Core tip: This study was carried out in a large unselected population to evaluate the characteristics of proton pump inhibitor (PPI) prescription and the adherence to the guidelines regulating the reimbursement limitations set forth by the Italian Drug Agency. A substantial number of patients who apparently do not meet prescription suitability conditions can be identified, but among non-PPI users on the contrary, it is possible to identify an equal number of patients for whom prescription would be suitable. According to our data the greatest problems in clinical decision originate in patients in antithrombotic therapy.