Lee AJ, Brenner L, Mourad B, Monteiro C, Vega KJ, Munoz JC. Gastrointestinal Kaposi’s sarcoma: Case report and review of the literature. World J Gastrointest Pharmacol Ther 2015; 6(3): 89-95 [PMID: 26261737 DOI: 10.4292/wjgpt.v6.i3.89]
Corresponding Author of This Article
Kenneth J Vega, MD, Division of Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, 920 Stanton L. Young Boulevard WP 1345, Oklahoma City, OK 73104, United States. kenneth-vega@ouhsc.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Pharmacol Ther. Aug 6, 2015; 6(3): 89-95 Published online Aug 6, 2015. doi: 10.4292/wjgpt.v6.i3.89
Gastrointestinal Kaposi’s sarcoma: Case report and review of the literature
Ann Joo Lee, Lacie Brenner, Bashar Mourad, Carmela Monteiro, Kenneth J Vega, Juan Carlos Munoz
Ann Joo Lee, Lacie Brenner, Juan Carlos Munoz, Division of Gastroenterology, Department of Medicine, University of Florida College of Medicine Jacksonville, Jacksonville, FL 32209, United States
Bashar Mourad, Department of Medicine, University of Florida College of Medicine Jacksonville, Jacksonville, FL 32209, United States
Carmela Monteiro, Department of Pathology, University of Florida College of Medicine Jacksonville, Jacksonville, FL 32209, United States
Kenneth J Vega, Division of Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States
Author contributions: Lee AJ and Mourad B collected the patient’s clinical data; Lee AJ, Brenner L and Munoz JC performed the endoscopy and obtained biopsies for diagnosis; Monteiro C analyzed the histopathology; Lee AJ, Munoz JC and Vega KJ performed the literature review and wrote the paper.
Supported by University of Florida College of Medicine Jacksonville.
Institutional review board statement: This research did not require approval by the University of Florida College of Medicine/Jacksonville institutional review board.
Informed consent statement: This research did not require an informed consent.
Conflict-of-interest statement: No conflict of interest exists for all authors in this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kenneth J Vega, MD, Division of Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, 920 Stanton L. Young Boulevard WP 1345, Oklahoma City, OK 73104, United States. kenneth-vega@ouhsc.edu
Telephone: +1-405-2715428 Fax: +1-405-2715803
Received: April 21, 2015 Peer-review started: April 24, 2015 First decision: June 3, 2015 Revised: June 21, 2015 Accepted: July 11, 2015 Article in press: July 14, 2015 Published online: August 6, 2015 Processing time: 109 Days and 9.6 Hours
Core Tip
Core tip: Gastrointestinal Kaposi’s sarcoma (GI-KS) is more common than originally thought and the majority of patients are asymptomatic and remain undiagnosed. Therefore, clinicians should maintain a high suspicion, especially among acquired immunodeficiency syndrome patients. Screening endoscopies are frequently performed and a recent retrospective study suggested using certain clinical factors (low CD4 cell count of < 100 cell/μL, men who have sex with men, and presence of cutaneous Kaposi’s) which may predict occurrence of GI-KS endoscopically. Endoscopy to detect GI-KS prior to clinical symptom development is desired as initiation of combined highly active antiretroviral therapy and liposomal doxorubicin therapy has shown to improve outcome.
