Systematic Reviews
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. May 6, 2015; 6(2): 22-27
Published online May 6, 2015. doi: 10.4292/wjgpt.v6.i2.22
Clinical relevance of intestinal peptide uptake
Hugh James Freeman
Hugh James Freeman, Department of Medicine, University of British Columbia, Vancouver V6T 1W5, Canada
Author contributions: Freeman HJ contributed all to this paper.
Conflict-of-interest: No conflict of interest declared.
Data sharing: No data sharing.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Hugh James Freeman, MD, CM, FRCPC, FACP, Department of Medicine, University of British Columbia, 2211 Wesbrook Mall, Vancouver V6T 1W5, Canada. hugfree@shaw.ca
Telephone: +1-604-8227216 Fax: +1-604-8227236
Received: October 9, 2014
Peer-review started: October 9, 2014
First decision: November 14, 2014
Revised: November 22, 2014
Accepted: March 30, 2015
Article in press: April 2, 2015
Published online: May 6, 2015
Processing time: 202 Days and 12.3 Hours
Core Tip

Core tip: Intestinal uptake of intact di-peptides and tri-peptides occurs by an independent epithelial transport process for protein assimilation. This carrier may also be used to absorb specific drugs and bacterial peptide products that may result in inflammatory disease.