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World J Gastrointest Pharmacol Ther. Aug 6, 2014; 5(3): 191-195
Published online Aug 6, 2014. doi: 10.4292/wjgpt.v5.i3.191
Published online Aug 6, 2014. doi: 10.4292/wjgpt.v5.i3.191
Statins and their role in acute pancreatitis: Case report and literature review
Denzil Etienne, Yousef Reda, Department of Medicine, SUNY Upstate Medical University, Syracuse, NY 13210, United States
Author contributions: Both the authors solely contributed to this paper.
Correspondence to: Denzil Etienne, MD, Department of Medicine, SUNY Upstate Medical University, 750 East Harrison Street, Syracuse, NY 13210, United States. denziletienne@gmail.com
Telephone: +1-315-4644480 Fax: +1-315-4644484
Received: May 14, 2014
Revised: June 20, 2014
Accepted: June 27, 2014
Published online: August 6, 2014
Processing time: 113 Days and 0.6 Hours
Revised: June 20, 2014
Accepted: June 27, 2014
Published online: August 6, 2014
Processing time: 113 Days and 0.6 Hours
Core Tip
Core tip: Statins may reduce the risk of developing an acute episode of pancreatitis through anti-inflammatory perturbation of the systemic inflammatory response pathway. However, it appears that these drugs may also carry a concomitant long-term risk of pancreatitis through a buildup of toxic metabolite/s.