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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Mar 5, 2025; 16(1): 97918
Published online Mar 5, 2025. doi: 10.4292/wjgpt.v16.i1.97918
Published online Mar 5, 2025. doi: 10.4292/wjgpt.v16.i1.97918
Insight into global burden of gastroesophageal reflux disease: Understanding its reach and impact
Nilanka Wickramasinghe, Department of Physiology, Faculty of Medicine, University of Colombo, Colombo 00800, Western Province, Sri Lanka
Niranga Manjuri Devanarayana, Department of Physiology, Faculty of Medicine, University of Kelaniya, Ragama 11010, Western Province, Sri Lanka
Author contributions: Wickramasinghe N and Devanarayana NM wrote the main manuscript text and prepared the figures and tables.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Niranga Manjuri Devanarayana, PhD, Professor, Department of Physiology, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama 11010, Western Province, Sri Lanka. niranga@kln.ac.lk
Received: June 12, 2024
Revised: October 29, 2024
Accepted: December 10, 2024
Published online: March 5, 2025
Processing time: 263 Days and 18.1 Hours
Revised: October 29, 2024
Accepted: December 10, 2024
Published online: March 5, 2025
Processing time: 263 Days and 18.1 Hours
Core Tip
Core Tip: Globally, the prevalence of gastroesophageal reflux disease (GERD) and GERD symptoms vary depending from country to country and region to region. Defining GERD and pinpointing its prevalence are problematic due to its diagnostic issues. However, understanding the differences in prevalence will help us identify the differences in associated risk factors, such as genetics and diet, that lead to an individual’s susceptibility to suffering from GERD and its symptoms.