Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Mar 20, 2024; 15(1): 90933
Published online Mar 20, 2024. doi: 10.4292/wjgpt.v15.i1.90933
New paradigm of oral rehydration in patients affected by irritable bowel syndrome with chronic diarrhea
Marco Chiarelli, Matilde De Simone, Gerardo Cioffi, Ugo Cioffi
Marco Chiarelli, Department of Emergency and Robotic Surgery, A. Manzoni Hospital–ASST Lecco, Lecco 23900, Italy
Matilde De Simone, Department of Surgery, University of Milan, Via F. Sforza 35, 20122 Milano, Milano 20122, Italy
Gerardo Cioffi, Department of Sciences and Technologies, Unisannio, Benevento 82100, Italy
Ugo Cioffi, Department of Surgery, University of Milan, Milano 20122, Italy
Author contributions: Chiarelli M, De Simone M, Cioffi G, and Cioffi U contributed equally to the manuscript and all read and accepted the final version.
Conflict-of-interest statement: All authors have no conflicts of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marco Chiarelli, MD, Researcher, Department of Emergency and Robotic Surgery, A. Manzoni Hospital–ASST Lecco, Lecco via Dell’Eremo 9/11, Lecco 23900, Italy. m.chiarelli@asst-lecco.it
Received: December 18, 2023
Peer-review started: December 18, 2023
First decision: January 11, 2024
Revised: January 20, 2024
Accepted: February 28, 2024
Article in press: February 28, 2024
Published online: March 20, 2024
Core Tip

Core Tip: Amino acid based solution has shown promising results in improving symptoms of chemotherapy related diarrhea. Irritable bowel syndrome with diarrhea is a very frequent gastrointestinal disorder. A recent study has been conducted to evaluate the clinical impact of the amino acid based medical beverage on the symptoms of diarrhea predominant irritable bowel syndrome with a real-life methodology. The amino acid based medical beverage seems to be well tolerated and improve gastrointestinal symptoms. The results of this study are very promising and the amino acid based solution will likely become part of the standard treatment for chronic recurrent diarrhea in the near future.