Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Mar 5, 2022; 13(2): 23-29
Published online Mar 5, 2022. doi: 10.4292/wjgpt.v13.i2.23
Hypereosinophilic syndrome presenting as eosinophilic gastroenteritis disorder and splinter hemorrhages: A case report
Ankith Bhasi, Itish Patnaik, Prasan Kumar Panda, Ashok Singh
Ankith Bhasi, Prasan Kumar Panda, Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh 249203, Uttarakhand, India
Itish Patnaik, Department of Gastroenterology, All India Institute of Medical Sciences, Rishikesh 249203, India
Ashok Singh, Department of Pathology, All India Institute of Medical Sciences, Rishikesh 249203, India
Author contributions: Bhasi A collected all data; Bhasi A, Panda PK and Singh A wrote the manuscript; Bhasi A, Patnaik I and Singh A contributed to the analysis; Bhasi A, Patnaik I, Panda PK, and Singh A contributed to approval; Patnaik I collected endoscopy data, reviewed the manuscript; Panda PK collected data, critically reviewed; Singh A collected pathology data.
Informed consent statement: The patient gave informed consent to share his clinical images and details including laboratory reports.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Prasan Kumar Panda, MBBS, MD, Associate Professor, Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh 249203, Uttarakhand, India. motherprasanna@rediffmail.com
Received: August 2, 2021
Peer-review started: August 2, 2021
First decision: October 15, 2021
Revised: October 31, 2021
Accepted: January 22, 2022
Article in press: January 22, 2022
Published online: March 5, 2022
Processing time: 211 Days and 8.4 Hours
Core Tip

Core Tip: This case reveals the wide spectrum of atypical manifestations of hypereosinophilic syndrome. Clinicians must be vigilant in order to diagnose primary instead of secondary eosinophilia as the former can cause diffuse organ infiltration and widespread tissue damage. Eosinophilic gastrointestinal disorder can present with involvement of all three layers of the gastrointestinal tract. Hypereosinophilic syndrome can also present with splinter hemorrhages. Prompt management of this lethal infiltrative disease provides a cure and avoids organ complications.