Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Jan 5, 2021; 12(1): 21-31
Published online Jan 5, 2021. doi: 10.4292/wjgpt.v12.i1.21
Clinical features and relative factors of constipation in a cohort of Chinese patients with Parkinson's disease
Bai-Hua Sun, Tao Wang, Nian-Ying Li, Qiong Wu, Jin Qiao
Bai-Hua Sun, Nian-Ying Li, Department ofNeurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China
Bai-Hua Sun, Department of Neurology, Xi'an Third Hospital, Xi'an 710021, Shaanxi Province, China
Tao Wang, Department ofNeurology, the Shaanxi Sengong Hospital, Xi'an 710300, Shaanxi Province, China
Qiong Wu, Jin Qiao, Department of Rehabilitation Medicine, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China
Author contributions: Qiao J and Wu Q designed, organized, and supervised the study and revised the manuscript; Sun BH, Wang T, and Li NY completed the data collection; Sun BH performed the statistical analysis and article writing.
Supported by Key Research and Development Program of Shaanxi Province, China, No. 2018SF-016 and No. 2020SF-153.
Institutional review board statement: The study was reviewed and approved by the ethics committee of the First Affiliated Hospital of Xi'an Jiaotong University (No. XJTU1AF2019LSK-037 and No. XJTU1AF2020LSK-182).
Conflict-of-interest statement: The authors has no potential conflicts of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin Qiao, MD, Professor, Department of Rehabilitation Medicine, the First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Xi'an 710061, Shaanxi Province, China. qiaojn123@163.com
Received: July 23, 2020
Peer-review started: July 23, 2020
First decision: September 24, 2020
Revised: September 28, 2020
Accepted: November 5, 2020
Article in press: November 5, 2020
Published online: January 5, 2021
Core Tip

Core Tip: This study aimed to determine the prevalence of constipation and analyze its clinical characteristics and relative risk factors in a cohort of Chinese patients with Parkinson's disease (PD). Our findings confirmed that constipation had a relatively high frequency in patients with PD. The patients with constipation had a higher incidence of depression, which led to worse quality of life.