Case Control Study
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Oct 15, 2019; 10(4): 67-74
Published online Oct 15, 2019. doi: 10.4292/wjgpt.v10.i4.67
Risk factors for recurrence after bowel resection for Crohn’s disease
Ze-Xian Chen, Yong-Le Chen, Xiao-Ming Huang, Xu-Tao Lin, Xiao-Wen He, Ping Lan
Ze-Xian Chen, Yong-Le Chen, Xiao-Wen He, Ping Lan, Department of Colorectal Surgery, the Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, Guangdong Province, China
Xiao-Ming Huang, Department of Hepatobiliary Surgery, the Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, Guangdong Province, China
Xu-Tao Lin, Department of Endoscopy Center, the Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, Guangdong Province, China
Author contributions: Chen ZX and Chen YL contributed equally to this work; all the authors contributed to the conception and design of the study; Chen ZX and Chen YL contributed to the collection of data; Huang XM and Lin XT contributed to the analysis and interpretation of the data; Chen ZX and Chen YL contributed to drafting the manuscript; He XW and Lan P contributed to critical revision of the manuscript for important intellectual content; all of the authors approved the final draft of the article.
Supported by Science and Technology Planning Project of Guangdong Province, No. 20160916; Medical Science Research Grant from the Health Department of Guangdong Province, No. A2018007.
Institutional review board statement: The study was approved by the ethics committee of the Sixth Affiliated Hospital, Sun Yat-Sen University.
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
STROBE statement: The authors have read the STROBE Statement, and the manuscript was prepared and revised according to the STROBE Statement.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ping Lan, PhD, Professor, Department of Colorectal Surgery, the Sixth Affiliated Hospital, Sun Yat-Sen University, 26 Yuancun Erheng Road, Guangzhou 510655, Guangdong Province, China. sumslp@163.com
Telephone: +86-20-38254009 Fax: +86-20-38254009
Received: May 16, 2019
Peer-review started: May 23, 2019
First decision: August 1, 2019
Revised: August 12, 2019
Accepted: September 20, 2019
Article in press: September 20, 2019
Published online: October 15, 2019
Processing time: 154 Days and 14.4 Hours
Core Tip

Core tip: Our study aimed at evaluating the risk factors for recurrence after bowel resection in Crohn’s disease. This study included 64 patients diagnosed Crohn’s disease and received intestinal resection. The result showed that diagnosis at younger age, disease behavior of penetrating and preoperative use of anti-tumor necrosis factor were independent prognostic factors for endoscopic recurrence, while complication with perianal lesions was an independent prognostic factor for clinical recurrence.