Published online Nov 8, 2020. doi: 10.4292/wjgpt.v11.i5.110
Peer-review started: March 4, 2020
First decision: April 12, 2020
Revised: April 27, 2020
Accepted: September 1, 2020
Article in press: September 1, 2020
Published online: November 8, 2020
Processing time: 247 Days and 4.6 Hours
Advanced gastric cancer (GC) often accompanies with liver metastasis. Though many physicians consider that radical surgeries are contraindicated for liver metastases from GC (LMGC). a smaller number of liver metastases without unresectable factors may be an indication for liver resection (LR).
The actual 5-year overall survival (OS) rate was previously documented as 0 to 0.37. Here, we presented the institutional indications for LR for LMGC, evaluated our own results.
In total, 30 patients underwent LR for LMGC during a 14-year period, and we evaluated the clinical, surgical, and oncological findings.
In all patients, radical surgery with intentional lymphadenectomy was performed for the primary GC. The median follow-up duration after the initial LR was 33.7 mo. The OS and recurrence-free survival rates after the initial LR were assessed. Also, we identified important factors for prognostic outcomes.
The 5-year OS and recurrence-free survival rates were 0.48 and 0.28, respectively. The median survival duration and recurrence-free duration after the initial LR were 16.8 and 8.6 mo, respectively. Although recurrence might develop after the initial LR, additional surgeries for recurrence clearly prolong survival. Pathological serosal invasion was an independent predictor of a poor prognostic outcome after the initial LR.
Our results of LR for LMGC seem acceptable. Pathological serosal invasion is important for poor prognostic outcomes.
Aggressive LR may be indicated for carefully selected patients with LMGC.