Rocha R, de J Santos G, Santana G. Influence of nutritional status in the postoperative period of patients with inflammatory bowel disease. World J Gastrointest Pharmacol Ther 2021; 12(5): 90-99 [PMID: 34616585 DOI: 10.4292/wjgpt.v12.i5.90]
Corresponding Author of This Article
Raquel Rocha, PhD, Professor, Department of Sciences of Nutrition, School of Nutrition, Federal University of Bahia, Avenida Araújo Pinho 32, Salvador 40110-150, Bahia, Brazil. raquelrocha2@yahoo.com.br
Research Domain of This Article
Nutrition & Dietetics
Article-Type of This Article
Evidence Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Pharmacol Ther. Sep 5, 2021; 12(5): 90-99 Published online Sep 5, 2021. doi: 10.4292/wjgpt.v12.i5.90
Influence of nutritional status in the postoperative period of patients with inflammatory bowel disease
Raquel Rocha, Geisa de J Santos, Genoile Santana
Raquel Rocha, Geisa de J Santos, Department of Sciences of Nutrition, School of Nutrition, Federal University of Bahia, Salvador 40110-150, Bahia, Brazil
Genoile Santana, Department of Life Sciences, State University of Bahia, Salvador 40110060, Bahia, Brazil
Author contributions: de J Santos G and Rocha R wrote the article; Rocha R and Santana G reviewed the article.
Supported byFAPESB (Fundação de Amparo à Pesquisa do Estado da Bahia).
Conflict-of-interest statement: Santana GO has served on advisory boards for Janssen, as a speaker for Abbvie, Ferring, Janssen, Takeda, and UCB Pharma, and has conducted research for Janssen, Lilly, Pfizer, Roche, and Takeda. The other authors declare that they have no conflicting interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Raquel Rocha, PhD, Professor, Department of Sciences of Nutrition, School of Nutrition, Federal University of Bahia, Avenida Araújo Pinho 32, Salvador 40110-150, Bahia, Brazil. raquelrocha2@yahoo.com.br
Received: February 22, 2021 Peer-review started: February 22, 2021 First decision: May 8, 2021 Revised: May 21, 2021 Accepted: August 30, 2021 Article in press: August 30, 2021 Published online: September 5, 2021 Processing time: 192 Days and 13 Hours
Abstract
Inflammatory bowel diseases (IBDs) are a group of chronic inflammatory diseases that affect the gastrointestinal tract, including Crohn's disease (CD) and ulcerative colitis. Surgery is a treatment option, and more than half of the patients with CD will undergo surgical interventions over the course of the disease. Postoperative complications are common in IBD patients, the most frequent being intra-abdominal sepsis, infection of the surgical site, and adynamic ileum, and nutritional status is a factor that can influence postoperative outcome. Recent studies have shown that malnutrition, obesity, sarcopenia, and myosteatosis are predictors of surgical complications. However, most were retrospective studies with small patient samples and heterogeneity of clinical and nutritional assessment methods, which limit the extrapolation of data. Therefore, knowing the pathophysiological mechanisms of IBD and identifying the best parameters for assessing nutritional status are essential for prompt implementation of adequate nutritional interventions.
Core Tip: Nutritional status influences the postsurgical results of patients with inflammatory bowel diseases (IBDs). Despite the limitations of previously published studies, malnutrition, obesity, sarcopenia, and myosteatosis were identified as negative predictive factors for postoperative complications in people diagnosed with IBDs.
