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World J Gastrointest Pathophysiol. Aug 15, 2016; 7(3): 276-282
Published online Aug 15, 2016. doi: 10.4291/wjgp.v7.i3.276
Pancreatic disorders in inflammatory bowel disease
Filippo Antonini, Raffaele Pezzilli, Lucia Angelelli, Giampiero Macarri
Filippo Antonini, Giampiero Macarri, Department of Gastroenterology, A.Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy
Raffaele Pezzilli, Department of Digestive Diseases and Internal Medicine, Sant’Orsola-Malpighi Hospital, 40138 Bologna, Italy
Lucia Angelelli, Medical Oncology, Mazzoni Hospital, 63100 Ascoli Piceno, Italy
Author contributions: Antonini F designed the research; Antonini F and Pezzilli R did the data collection and analyzed the data; Antonini F, Pezzilli R and Angelelli L wrote the paper; Macarri G revised the paper and granted the final approval.
Conflict-of-interest statement: The authors declare no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Filippo Antonini, MD, Department of Gastroenterology, A.Murri Hospital, Polytechnic University of Marche, Ospedale “A.Murri”, 63900 Fermo, Italy. filippore@yahoo.it
Telephone: +39-0734-6252249 Fax: +39-0734-6252252
Received: May 24, 2016
Peer-review started: May 25, 2016
First decision: June 17, 2016
Revised: July 8, 2016
Accepted: July 20, 2016
Article in press: July 22, 2016
Published online: August 15, 2016
Processing time: 78 Days and 13.7 Hours
Core Tip

Core tip: Pancreatic disorders are not uncommon in patients with inflammatory bowel disease (IBD). The most frequent manifestation is acute pancreatitis (AP). Causes of AP are mainly a concomitant biliary lithiasis or drugs used in the treatment of IBD. However for some IBD-related pancreatitis, idiopathic by definition, where no relationship with lithiasis or drugs can be recognized, a direct pancreatic damage would be hypothesized.