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World J Gastrointest Pathophysiol. Aug 15, 2014; 5(3): 213-227
Published online Aug 15, 2014. doi: 10.4291/wjgp.v5.i3.213
Escherichia coli in chronic inflammatory bowel diseases: An update on adherent invasive Escherichia coli pathogenicity
Margarita Martinez-Medina, Librado Jesus Garcia-Gil
Margarita Martinez-Medina, Librado Jesus Garcia-Gil, Laboratory of Molecular Microbiology, Biology Department, University of Girona, E-17071 Girona, Spain
Author contributions: Martinez-Medina M wrote the paper; Garcia-Gil LJ revised the paper.
Correspondence to: Margarita Martinez-Medina, PhD, Laboratory of Molecular Microbiology, Biology Department, University of Girona, Campus de Montilivi, E-17071 Girona, Spain. marga.martinez@udg.edu
Telephone: +34-972-418175 Fax: +34-972-418150
Received: January 28, 2014
Revised: April 8, 2014
Accepted: May 29, 2014
Published online: August 15, 2014
Processing time: 218 Days and 13.7 Hours
Core Tip

Core tip: In this review we critically revise the findings on Escherichia coli (E. coli) populations associated with Crohn’s disease and ulcerative colitis. Then we focus on adherent invasive E. coli (AIEC), especially in its mechanisms of pathogenicity and epidemiology. We discuss about AIEC disease- and host-specificity and we underline the importance of discovering specific molecular tools to detect AIEC for further epidemiologic studies. Finally we point out to a putative role of diet on AIEC gut colonization.