Phillip V, Steiner JM, Algül H. Early phase of acute pancreatitis: Assessment and management. World J Gastrointest Pathophysiol 2014; 5(3): 158-168 [PMID: 25133018 DOI: 10.4291/wjgp.v5.i3.158]
Corresponding Author of This Article
Hana Algül, MD, MPH, II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technische Universität München, Ismaninger Straße 22, 81675 München, Germany. hana.alguel@lrz.tum.de
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Topic Highlight
Open-Access Policy of This Article
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World J Gastrointest Pathophysiol. Aug 15, 2014; 5(3): 158-168 Published online Aug 15, 2014. doi: 10.4291/wjgp.v5.i3.158
Early phase of acute pancreatitis: Assessment and management
Veit Phillip, Jörg M Steiner, Hana Algül
Veit Phillip, Jörg M Steiner, Hana Algül, II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, 81675 München, Germany
Jörg M Steiner, Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843-4474, United States
Author contributions: Phillip V and Algül H collected and analyzed the literature; Phillip V prepared the original draft; Steiner JM and Algül H supplemented the material and revised the manuscript; all authors approved the final version of the paper to be published.
Correspondence to: Hana Algül, MD, MPH, II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technische Universität München, Ismaninger Straße 22, 81675 München, Germany. hana.alguel@lrz.tum.de
Telephone: +49-89-41405215 Fax: +49-89-41406794
Received: January 29, 2014 Revised: March 25, 2014 Accepted: May 29, 2014 Published online: August 15, 2014 Processing time: 217 Days and 14.1 Hours
Core Tip
Core tip: Acute pancreatitis is a frequent and potentially life-threatening disease. Therapy is currently mostly symptomatic with fluid resuscitation, pain management, and early oral feeding. Vigorous fluid resuscitation remains a cornerstone of early management of acute pancreatitis. Cross-sectional imaging during the early phase of evaluation has not been associated with improvement in outcome. There is no role for prophylactic antibiotics in the management of the early phase of acute pancreatitis (AP). Enteral nutrition in AP can reduce mortality, systemic infections, and multiorgan dysfunction compared to parenteral nutrition. Immediate endoscopic retrograde cholangiography is indicated only in patients with biliary pancreatitis with common bile duct obstruction and cholangitis.
