Del Chiaro M, Rangelova E, Ansorge C, Blomberg J, Segersvärd R. Impact of body mass index for patients undergoing pancreaticoduodenectomy. World J Gastrointest Pathophysiol 2013; 4(2): 37-42 [PMID: 23755369 DOI: 10.4291/wjgp.v4.i2.37]
Corresponding Author of This Article
Marco Del Chiaro, MD, PhD, Division of Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institute at Karolinska University Hospital, Huddinge K53, 14186 Stockholm, Sweden. marco.del-chiaro@karolinska.se
Research Domain of This Article
Surgery
Article-Type of This Article
Brief Article
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World J Gastrointest Pathophysiol. May 15, 2013; 4(2): 37-42 Published online May 15, 2013. doi: 10.4291/wjgp.v4.i2.37
Impact of body mass index for patients undergoing pancreaticoduodenectomy
Marco Del Chiaro, Elena Rangelova, Christoph Ansorge, John Blomberg, Ralf Segersvärd
Marco Del Chiaro, Elena Rangelova, Christoph Ansorge, John Blomberg, Ralf Segersvärd, Division of Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institute at Karolinska University Hospital, 14186 Stockholm, Sweden
Author contributions: Del Chiaro M designed the study, analyzed the results and operates the patients; Rangelova E, Ansorge C and Blomberg J operated the patients; Segersvärd R contributed to writing the paper and operating the patients.
Supported by Division of Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institute at Karolinska University Hospital, Stockholm, Sweden
Correspondence to: Marco Del Chiaro, MD, PhD, Division of Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institute at Karolinska University Hospital, Huddinge K53, 14186 Stockholm, Sweden. marco.del-chiaro@karolinska.se
Telephone: +46-8-58582340 Fax: +46-8-58582340
Received: January 10, 2013 Revised: April 9, 2013 Accepted: April 13, 2013 Published online: May 15, 2013 Processing time: 147 Days and 17.7 Hours
Core Tip
Core tip: In the last decades, the number of overweight individuals has increased dramatically in Western countries. No data are available in the literature that show clearly whether this comorbidity has an impact on short-term or long-term outcomes in these patients or on procedure-related costs. Some studies have shown that pancreatectomies in overweight patients are associated with an increased risk of post-operative complications. The data are even more confusing regarding long-term and oncologic outcomes. In our study, based on a large series of consecutive pancreaticoduodenectomies (PD) performed in a high volume center for pancreatic surgery, we showed that body mass index (BMI) is a risk factor for intra-operative bleeding and post-operative pancreatic fistula, but does not increase the overall morbidity and have no impact on survival of patients with pancreatic ductal adenocarcinoma. Based on these results, BMI should not be considered, per-se, an exclusion criteria for candidates for PD.
