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World J Gastrointest Pathophysiol. Dec 15, 2012; 3(6): 99-101
Published online Dec 15, 2012. doi: 10.4291/wjgp.v3.i6.99
Published online Dec 15, 2012. doi: 10.4291/wjgp.v3.i6.99
Sphingolipids in intestine and liver: How to analyze?
Nikolaus Gassler, Institute of Pathology, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany
Author contributions: Gassler N solely contributed to this paper.
Correspondence to: Dr. Nikolaus Gassler, MA, Professor, Institute of Pathology, RWTH Aachen University, Pauwelsstraße, 30, 52074 Aachen, Germany. ngassler@ukaachen.de
Telephone: +49-241-8088897 Fax: +49-241-8082439
Received: August 26, 2011
Revised: November 26, 2012
Accepted: December 10, 2012
Published online: December 15, 2012
Revised: November 26, 2012
Accepted: December 10, 2012
Published online: December 15, 2012
Abstract
Identification and quantification of lipids, in particular sphingolipids from intestine and liver, using multidimensional mass spectrometry has dramatically improved our understanding of lipid-based molecular pathways and signaling. The editorial gives a short overview about basic technical approaches to characterize lipids from intestine and liver.
Keywords: Intestine; Lipids; Liver; Mass spectrometry