Nomogram for predicting short-term response to anti-vascular endothelial growth factor treatment in neovascular age-related macular degeneration: An observational study

Table 1 Univariate and multivariate analyses of clinical and optical coherence tomography angiography characteristics associated with response to anti-vascular endothelial growth factor therapy

Characteristic	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)	P value
Age (years)	0.997 (0.947-1.049)	0.901
Gender (male)	0.777 (0.237-2.356)	0.663
Hypertension	1.920 (0.649-6.229)	0.252
Diabetes mellitus	0.650 (0.13-3.571)	0.596
Smoking habits (active and former smoker)	0.602 (0.198-1.852)	0.368
Alcohol consumption (active and former drinker)	0.917 (0.292-3.072)	0.883
Morphological feature (long linear vessels)	1.029 (0.190-5.409)	0.973
Morphological feature (indistinct network)	1.187 (0.271-4.694)	0.810
Area (mm2)	0.448 (0.053-3.733)	0.444
Fractal dimension	0.000 (0.000-6.103)	0.093	0.000 (0.000-486.4)	0.195
Branch number	0.999 (0.998-1.000)	0.171	1.004 (0.995-1.014)	0.362
Junction number	0.997 (0.991-1.001)	0.179	1.013 (0.977-1.056)	0.489
Number of end-point voxels	1.000 (0.999-1.001)	0.517
Number of junction voxels	0.999 (0.999-1.000)	0.047	0.997 (0.993-0.999)	0.010
Number of slab voxels	1.000 (0.999-1.000)	0.214
Average branch length (mm)	1.000 (0.998-1.001)	0.601
Maximum branch length (mm)	1.000 (0.999-1.001)	0.575
Longest shortest path (mm)	1.000 (0.999-1.000)	0.555

OR: Odds ratio; CI: Confidence interval.