Basic Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Apr 28, 2017; 9(4): 199-205
Published online Apr 28, 2017. doi: 10.4329/wjr.v9.i4.199
Gd-EOB-DTPA based magnetic resonance imaging for predicting liver response to portal vein embolization
Janio Szklaruk, Gustavo Luersen, Jingfei Ma, Wei Wei, Michelle Underwood
Janio Szklaruk, Jingfei Ma, Wei Wei, Michelle Underwood, Department of Diagnostic Radiology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States
Gustavo Luersen, Hospital Moinhos de Vento, Rua Goncalo de Carvalho, Porto Alegre, RS 90035-170, Brazil
Author contributions: All authors contributed to the study design, manuscript preparation, data analysis and data acquisition (except Wei W he did not work on Data Acquisition); the statistical methods were reviewed by Wei W who is a Principal statistical analyst.
Supported by The NIH/NCI and used the Department of Biostatistics Resource Group, No. P30CA016672.
Institutional review board statement: This study was approved by the University of Texas MD Anderson Cancer Center Institutional Review Board as a prospective project.
Conflict-of-interest statement: All others declare that they have nothing to disclose except for Dr. Jingfei Ma. Dr. Ma has ongoing financial relationships with GE Healthcare and Siemens Healthcare and there are no family members that present a potential conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Janio Szklaruk, MD, PhD, Professor, Department of Diagnostic Radiology, the University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1473, Houston, TX 77030, United States. jszklaru@mdanderson.org
Telephone: +1-713-7453230 Fax: +1-713-7451302
Received: August 26, 2016
Peer-review started: August 29, 2016
First decision: December 13, 2016
Revised: January 11, 2017
Accepted: February 28, 2017
Article in press: March 2, 2017
Published online: April 28, 2017
Processing time: 244 Days and 19.7 Hours
Core Tip

Core tip: Our hypothesis was that the degree of enhancement of the liver during the hepatobiliary phase will correlate with the degree of liver response to portal vein embolization. This will be able to be used as a screen method for patients scheduled for portal vein embolization (PVE). The use of Gd-EOB-DTPA in the assessment of liver function has been correlated with clinical assessment of liver function classification. We evaluated the correlation between degree of kinetic growth (kGR) of the liver following PVE liver and the enhancement of the during the hepatobiliary phase of contrast administration. There was no correlation between the degree of enhancement during the hepatobiliary phase and kGR.