Review
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Dec 28, 2017; 9(12): 416-425
Published online Dec 28, 2017. doi: 10.4329/wjr.v9.i12.416
Dynamic contrast-enhanced magnetic resonance imaging of prostate cancer: A review of current methods and applications
Yousef Mazaheri, Oguz Akin, Hedvig Hricak
Yousef Mazaheri, Department of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, United States
Oguz Akin, Hedvig Hricak, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, United States
Author contributions: All authors are the guarantors of integrity of entire study; Mazaheri Y designed the study; Mazaheri Y and Akin O performed data analysis/interpretation; Mazaheri Y and Akin O performed the literature research; all authors contributed to manuscript drafting or manuscript revision for important intellectual content; all authors gave manuscript final version approval and manuscript editing; all authors take responsibility for the integrity of the data and the accuracy of the data analysis.
Conflict-of-interest statement: This manuscript is not published anywhere else; all authors conform that there is no conflict of interests (including none for related to commercial, personal, political, intellectual, or religious interests).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Yousef Mazaheri, PhD, Department of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, United States. mazahery@mskcc.org
Telephone: +1-646-8884520 Fax: +1-646-8885139
Received: May 17, 2017
Peer-review started: May 19, 2017
First decision: July 3, 2017
Revised: August 3, 2017
Accepted: October 17, 2017
Article in press: October 17, 2017
Published online: December 28, 2017
Processing time: 222 Days and 13 Hours
Core Tip

Core tip: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of prostate cancer can characterize tissue vascularity with important clinical application including aid in the detection, localization and staging, assessment of tumor aggressiveness, and assessment of treatment response. The current lack of standardized acquisition and analysis methods should be addressed to encourage more wide spread use of DCE-MRI in prostate cancer imaging.