Padole A, Sainani N, Lira D, Khawaja RDA, Pourjabbar S, Lo Gullo R, Otrakji A, Kalra MK. Assessment of sub-milli-sievert abdominal computed tomography with iterative reconstruction techniques of different vendors. World J Radiol 2016; 8(6): 618-627 [PMID: 27358690 DOI: 10.4329/wjr.v8.i6.618]
Corresponding Author of This Article
Atul Padole, MD, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 25 New Chardon St, 4th Floor, Boston, MA 02114, United States. apadole@mgh.harvard.edu
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Prospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Radiol. Jun 28, 2016; 8(6): 618-627 Published online Jun 28, 2016. doi: 10.4329/wjr.v8.i6.618
Assessment of sub-milli-sievert abdominal computed tomography with iterative reconstruction techniques of different vendors
Atul Padole, Nisha Sainani, Diego Lira, Ranish Deedar Ali Khawaja, Sarvenaz Pourjabbar, Roberto Lo Gullo, Alexi Otrakji, Mannudeep K Kalra
Atul Padole, Nisha Sainani, Diego Lira, Ranish Deedar Ali Khawaja, Sarvenaz Pourjabbar, Roberto Lo Gullo, Alexi Otrakji, Mannudeep K Kalra, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, United States
Nisha Sainani, Department of Radiology, Brigham and Women’s Hospital, Boston, MA 02115, United States
Author contributions: Padole A, Khawaja RDA and Pourjabbar S were involved in patient recruitment and objective measurement; Padole A and Kalra MK wrote the manuscript; Sainani N and Lira D were the readers of the study; Lo Gullo R and Otrakji A were involved in blinding of study; Kalra MK helped in consenting patients and designing the study.
Institutional review board statement: The Human Research Committee of our Institutional Review Board (IRB) approved this Health Insurance Portability and Accountability Act (HIPAA) compliant prospective clinical study.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: None of the authors have any pertinent financial disclosures.
Data sharing statement: All the study participants gave written informed consent for data sharing.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Atul Padole, MD, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 25 New Chardon St, 4th Floor, Boston, MA 02114, United States. apadole@mgh.harvard.edu
Telephone: +1-617-6435076 Fax: +1-617-6430111
Received: November 28, 2015 Peer-review started: November 30, 2015 First decision: December 28, 2015 Revised: January 8, 2016 Accepted: March 7, 2016 Article in press: March 9, 2016 Published online: June 28, 2016 Processing time: 203 Days and 12.4 Hours
Core Tip
Core tip: We assessed the performance of abdominal computed tomography (CT) acquired at sub-milli-Sievert radiation dose to the standard of care CT. A total of 66 subjects were scanned on three different multi-detector CT scanners at sub-milli-Sievert radiation dose [or CT dose index volume (CTDIvol) of 1.3 mGy]. Images were reconstructed with vendor-specific and vendor-neutral iterative reconstruction techniques (IRTs). We compared the clinical diagnostic performance of vendor specific and vendor neutral IRTs at sub-milli-Sievert radiation dose to the standard of care CT. We found that regardless of the IRTs and multi-detector CT vendors, CTDIvol of 1.3 mGy or sub-mill-sievert radiation dose did not provide sufficient clinical diagnostic performance for abdominal CT.
