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World J Radiol. Jun 28, 2014; 6(6): 366-373
Published online Jun 28, 2014. doi: 10.4329/wjr.v6.i6.366
Published online Jun 28, 2014. doi: 10.4329/wjr.v6.i6.366
Use of stereotactic radiosurgery in the treatment of gynecologic malignancies: A review
Beverly Long, Department of Obstetrics and Gynecology, University of California, Irvine Medical Center, Orange, CA 92868, United States
Ramez N Eskander, Krishnansu S Tewari, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, Irvine Medical Center, Orange, CA 92868, United States
Author contributions: Long B and Eskander RN performed the literature review and wrote the manuscript; Tewari KS provided expert opinion and final review and final edits.
Correspondence to: Ramez N Eskander, MD, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, Irvine Medical Center, 101 The City Drive, Building 56, Room 260, Orange, CA 92868, United States. eskander@uci.edu
Telephone: +1-714-4566026 Fax: +1-714-4567754
Received: December 29, 2013
Revised: April 1, 2014
Accepted: April 17, 2014
Published online: June 28, 2014
Processing time: 181 Days and 1.5 Hours
Revised: April 1, 2014
Accepted: April 17, 2014
Published online: June 28, 2014
Processing time: 181 Days and 1.5 Hours
Core Tip
Core tip: Stereotactic radiosurgery is a novel treatment modality in gynecologic oncology. Its use has been reported for inoperable primary tumors, recurrent tumors in or near irradiated fields, and isolated pelvic nodal metastases. Associated toxicities are usually mild. Though further research is needed to establish the role of SRS in gynecologic oncology, it represents an important second line therapy in appropriately selected patients.